DNA damage resulting from the oxidation of hydroquinone by copper: Role for a cu(II)/cu(i) redox cycle and reactive oxygen generation

Pharmacology, Toxicology and Pharmaceutical Science

• Cuprous Ion 100%
• Hydroquinone 100%
• Hydrogen Peroxide 31%
• Cysteine 13%
• Singlet Oxygen 13%
• Catalase 9%
• Myeloperoxidase 9%
• Hydroxyl Radical 9%
• Benzoquinone 9%
• Epileptic Absence 4%
• Glutathione 4%
• Leukemia 4%
• Scavenger 4%
• Bone Marrow Toxicity 4%
• Dithiothreitol 4%
• Plasmid DNA 4%
• Ferric Ion 4%
• Catechol 4%
• Phenol 4%
• 1,2,4 Benzenetriol 4%

Keyphrases

• Oxygen Generation 100%
• Copper Peroxide 4%
• Redox Mechanism 4%
• Peroxide Complex 4%

Chemistry

• L-Cysteine 15%
• Benzenetriol 5%