Divalproex Sodium and Other Medications for Headache Following Craniotomy for Acoustic Neuroma

Nelson Hendler, Ann Cashen, Candis Morrison, Donlin Long, Michael Holliday

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Multiple pharmacologic agents were used in attempt to relieve a constant and severe headache in a 47‐year‐old patient following craniotomy for removal of an acoustic neuroma. Possible etiologies for the unremitting headache are presented. Response to various pharmacologic agents are listed and discussed. During the postoperative course of two surgeries on this patient, it was possible to propose an etiology for the headache by analyzing the mechanisms of each therapeutic agent, along with the patient's response. Divalproex sodium provided complete relief, suggesting the headache is attributable to cell membrane instability.

Original languageEnglish (US)
Pages (from-to)490-493
Number of pages4
JournalHeadache: The Journal of Head and Face Pain
Volume35
Issue number8
DOIs
StatePublished - Sep 1995

Keywords

  • Headache
  • acoustic neuroma
  • postcraniotomy headache

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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