Distortion matrix concept for deep imaging in optical microscopy

V. Barolle, P. Balondrade, A. Badon, K. Irsch, A. C. Boccara, M. Fink, A. Aubry

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In optical imaging, light propagation is affected by the medium inhomogeneities. Adaptive optics has been employed to compensate for sample-induced aberrations but the field-of-view is often limited to a single isoplanatic patch. Here, we propose a non-invasive approach based on the distortion matrix concept. This matrix basically connects any focusing point with the distorted part of its wave-front in reflection. Its time-reversal and entropy analysis allows to correct for high-order aberrations over multiple isoplanatic areas. We demonstrate a Strehl ratio enhancement up to 2500 and a diffraction-limited resolution until a depth of ten scattering mean free paths through an opaque cornea.

Original languageEnglish (US)
Title of host publicationAdaptive Optics
Subtitle of host publicationAnalysis, Methods and Systems, AOMS 2020
PublisherThe Optical Society
ISBN (Electronic)9781557528209
StatePublished - 2020
Externally publishedYes
EventAdaptive Optics: Analysis, Methods and Systems, AOMS 2020 - Part of Imaging and Applied Optics Congress 2020 - Virtual, Online, United States
Duration: Jun 22 2020Jun 26 2020

Publication series

NameOptics InfoBase Conference Papers

Conference

ConferenceAdaptive Optics: Analysis, Methods and Systems, AOMS 2020 - Part of Imaging and Applied Optics Congress 2020
Country/TerritoryUnited States
CityVirtual, Online
Period6/22/206/26/20

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials

Fingerprint

Dive into the research topics of 'Distortion matrix concept for deep imaging in optical microscopy'. Together they form a unique fingerprint.

Cite this