Distortion-free freehand-scanning OCT implemented with real-time scanning speed variance correction

Xuan Liu, Yong Huang, Jin U. Kang

Research output: Contribution to journalArticlepeer-review


Hand-held OCT systems that offer physicians greater freedom to access imaging sites of interest could be useful for many clinical applications. In this study, by incorporating the theoretical speckle model into the decorrelation function, we have explicitly correlated the crosscorrelation coefficient to the lateral displacement between adjacent A-scans. We used this model to develop and study a freehand-scanning OCT system capable of real-time scanning speed correction and distortion-free imaging-for the first time to the best our knowledge. To validate our model and the system, we performed a series of calibration experiments. Experimental results show that our method can extract lateral scanning distance. In addition, using the manually scanned hand-held OCT system we obtained OCT images from various samples by freehand manual scanning, including images obtained from human in vivo.

Original languageEnglish (US)
Pages (from-to)16567-16583
Number of pages17
JournalOptics Express
Issue number15
StatePublished - Jul 16 2012
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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