Distinct Mechanisms of Tumor Resistance to NK Killing: Of Mice and Men

Drew M. Pardoll

doi:10.1016/j.immuni.2015.04.007

Distinct Mechanisms of Tumor Resistance to NK Killing: Of Mice and Men

Drew M. Pardoll

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Tumors cells can release natural killer (NK) cell ligands for activating receptor NKG2D that are thought to inhibit NK cell function. In a recent issue of Science, Deng etal. (2015) show that, unexpectedly, a soluble NKG2D ligand can enhance anti-tumor NK cell activity.

Original language	English (US)
Pages (from-to)	605-606
Number of pages	2
Journal	Immunity
Volume	42
Issue number	4
DOIs	https://doi.org/10.1016/j.immuni.2015.04.007
State	Published - Apr 21 2015

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2015.04.007

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title = "Distinct Mechanisms of Tumor Resistance to NK Killing: Of Mice and Men",

abstract = "Tumors cells can release natural killer (NK) cell ligands for activating receptor NKG2D that are thought to inhibit NK cell function. In a recent issue of Science, Deng etal. (2015) show that, unexpectedly, a soluble NKG2D ligand can enhance anti-tumor NK cell activity.",

author = "Pardoll, \{Drew M.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

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day = "21",

doi = "10.1016/j.immuni.2015.04.007",

language = "English (US)",

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TY - JOUR

T1 - Distinct Mechanisms of Tumor Resistance to NK Killing

T2 - Of Mice and Men

AU - Pardoll, Drew M.

PY - 2015/4/21

Y1 - 2015/4/21

N2 - Tumors cells can release natural killer (NK) cell ligands for activating receptor NKG2D that are thought to inhibit NK cell function. In a recent issue of Science, Deng etal. (2015) show that, unexpectedly, a soluble NKG2D ligand can enhance anti-tumor NK cell activity.

AB - Tumors cells can release natural killer (NK) cell ligands for activating receptor NKG2D that are thought to inhibit NK cell function. In a recent issue of Science, Deng etal. (2015) show that, unexpectedly, a soluble NKG2D ligand can enhance anti-tumor NK cell activity.

UR - https://www.scopus.com/pages/publications/84928202804

UR - https://www.scopus.com/pages/publications/84928202804#tab=citedBy

U2 - 10.1016/j.immuni.2015.04.007

DO - 10.1016/j.immuni.2015.04.007

M3 - Short survey

C2 - 25902479

AN - SCOPUS:84928202804

SN - 1074-7613

VL - 42

SP - 605

EP - 606

JO - Immunity

JF - Immunity

IS - 4

ER -

Distinct Mechanisms of Tumor Resistance to NK Killing: Of Mice and Men

Abstract

ASJC Scopus subject areas

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