TY - JOUR
T1 - Disparities in mortality among adults with and without diabetes by sex and race
AU - Mansour, Omar
AU - Golden, Sherita H.
AU - Yeh, Hsin Chieh
N1 - Funding Information:
This work was supported in part by grant P30DK079637 from the National Institute of Diabetes and Digestive and Kidney Diseases . The funding source had no role in the design and conduct of the study, analysis or interpretation of the data, and preparation or final approval of the manuscript prior to publication.
Publisher Copyright:
© 2019 Elsevier Inc.
PY - 2020/3
Y1 - 2020/3
N2 - Objective: The aim of this study was to examine whether the reduction in the mortality gap between individuals with and without diabetes varies by sex and race/ethnicity. Methods: We analyzed data in adults from the National Health and Nutrition Examination Survey (NHANES) 1999–2010 and their linked mortality data through 2015. Cox proportional hazards models were used to examine the risk of all-cause and cause-specific mortality among participants with diabetes as compared to those without diabetes by sex and race/ethnicity in 1999–2004 and 2005–2010. Results: The risk of all-cause mortality was significantly higher in women with diabetes compared to those without diabetes in both study periods (HR 1.6, 95% CI: 1.2, 2.2; HR 1.5, 95% CI: 1.1, 2.0). Among men, the risk of all-cause mortality was significantly higher in men with compared to men without diabetes in 1999–2004 but not in 2005–2010. There was no significant association between diabetes and CVD mortality among men in 2005–2010, while the association was significant among women in both study periods (HR 2.5, 95% CI: 1.6, 3.7; HR 2.8, 95% CI: 1.3, 5.9). The association between diabetes and all-cause mortality was similar across racial/ethnic groups in 1999–2004, but was significantly higher among non-Hispanic blacks and Mexican Americans in 2005–2010. Conclusions: Progress in reducing mortality among individuals with diabetes has been more significant among men and non-Hispanic whites. Sex and racial/ethnic disparities in mortality among individuals with diabetes still persist.
AB - Objective: The aim of this study was to examine whether the reduction in the mortality gap between individuals with and without diabetes varies by sex and race/ethnicity. Methods: We analyzed data in adults from the National Health and Nutrition Examination Survey (NHANES) 1999–2010 and their linked mortality data through 2015. Cox proportional hazards models were used to examine the risk of all-cause and cause-specific mortality among participants with diabetes as compared to those without diabetes by sex and race/ethnicity in 1999–2004 and 2005–2010. Results: The risk of all-cause mortality was significantly higher in women with diabetes compared to those without diabetes in both study periods (HR 1.6, 95% CI: 1.2, 2.2; HR 1.5, 95% CI: 1.1, 2.0). Among men, the risk of all-cause mortality was significantly higher in men with compared to men without diabetes in 1999–2004 but not in 2005–2010. There was no significant association between diabetes and CVD mortality among men in 2005–2010, while the association was significant among women in both study periods (HR 2.5, 95% CI: 1.6, 3.7; HR 2.8, 95% CI: 1.3, 5.9). The association between diabetes and all-cause mortality was similar across racial/ethnic groups in 1999–2004, but was significantly higher among non-Hispanic blacks and Mexican Americans in 2005–2010. Conclusions: Progress in reducing mortality among individuals with diabetes has been more significant among men and non-Hispanic whites. Sex and racial/ethnic disparities in mortality among individuals with diabetes still persist.
KW - CVD morality
KW - Disparity
KW - T2D
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U2 - 10.1016/j.jdiacomp.2019.107496
DO - 10.1016/j.jdiacomp.2019.107496
M3 - Article
C2 - 31784284
AN - SCOPUS:85076550131
SN - 1056-8727
VL - 34
JO - Journal of Diabetes and its Complications
JF - Journal of Diabetes and its Complications
IS - 3
M1 - 107496
ER -