Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

H. H. Garcia; G. Herrera; R. H. Gilman; V. C.W. Tsang; J. B. Pilcher; J. F. Diaz; E. J. Candy; E. Miranda; J. Naranjo; P. Torres; C. Gallo; C. Careamo; M. Verastegui; T. Montenegro; M. Alvarez; C. Evans; A. E. Gonzales; M. Castro; A. Guerron

doi:10.4269/ajtmh.1994.50.152

Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

H. H. Garcia, G. Herrera, R. H. Gilman, V. C.W. Tsang, J. B. Pilcher, J. F. Diaz, E. J. Candy, E. Miranda, J. Naranjo, P. Torres, C. Gallo, C. Careamo, M. Verastegui, T. Montenegro, M. Alvarez, C. Evans, A. E. Gonzales, M. Castro, A. Guerron

Research output: Contribution to journal › Article › peer-review

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Abstract

Serum samples from sequential patients who underwent cerebral computed axial tomography (CT) scan in a Peruvian radiologic clinic were tested by the highly sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB) test to detect antibodies to Taenia solium. The results of the EITB test were compared with those obtained by CT scan for the diagnosis of neurocysticercosis. Of the 383 patients sampled, 32 (8%) were seropositive. The results of CT and EITB were frequently discrepant. When compared with the EITB assay, the CT scan was 44% sensitive and 95% specific. The sensitivity of CT increased to 63% if less specific images (single calcifications, granulomas, or hydrocephalus) were included. The CT scan for diagnosis of cysticercosis can best be used in conjunction with a reliable serologic test such as the EITB.

Original language	English (US)
Pages (from-to)	152-157
Number of pages	6
Journal	American Journal of Tropical Medicine and Hygiene
Volume	50
Issue number	2
DOIs	https://doi.org/10.4269/ajtmh.1994.50.152
State	Published - 1994
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Infectious Diseases
Virology

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Garcia, H. H., Herrera, G., Gilman, R. H., Tsang, V. C. W., Pilcher, J. B., Diaz, J. F., Candy, E. J., Miranda, E., Naranjo, J., Torres, P., Gallo, C., Careamo, C., Verastegui, M., Montenegro, T., Alvarez, M., Evans, C., Gonzales, A. E., Castro, M., & Guerron, A. (1994). Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis. American Journal of Tropical Medicine and Hygiene, 50(2), 152-157. https://doi.org/10.4269/ajtmh.1994.50.152

Garcia, HH, Herrera, G, Gilman, RH, Tsang, VCW, Pilcher, JB, Diaz, JF, Candy, EJ, Miranda, E, Naranjo, J, Torres, P, Gallo, C, Careamo, C, Verastegui, M, Montenegro, T, Alvarez, M, Evans, C, Gonzales, AE, Castro, M & Guerron, A 1994, 'Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis', American Journal of Tropical Medicine and Hygiene, vol. 50, no. 2, pp. 152-157. https://doi.org/10.4269/ajtmh.1994.50.152

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title = "Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis",

abstract = "Serum samples from sequential patients who underwent cerebral computed axial tomography (CT) scan in a Peruvian radiologic clinic were tested by the highly sensitive and specific enzyme-linked immunoelectrotransfer blot (EITB) test to detect antibodies to Taenia solium. The results of the EITB test were compared with those obtained by CT scan for the diagnosis of neurocysticercosis. Of the 383 patients sampled, 32 (8%) were seropositive. The results of CT and EITB were frequently discrepant. When compared with the EITB assay, the CT scan was 44% sensitive and 95% specific. The sensitivity of CT increased to 63% if less specific images (single calcifications, granulomas, or hydrocephalus) were included. The CT scan for diagnosis of cysticercosis can best be used in conjunction with a reliable serologic test such as the EITB.",

author = "Garcia, {H. H.} and G. Herrera and Gilman, {R. H.} and Tsang, {V. C.W.} and Pilcher, {J. B.} and Diaz, {J. F.} and Candy, {E. J.} and E. Miranda and J. Naranjo and P. Torres and C. Gallo and C. Careamo and M. Verastegui and T. Montenegro and M. Alvarez and C. Evans and Gonzales, {A. E.} and M. Castro and A. Guerron",

year = "1994",

doi = "10.4269/ajtmh.1994.50.152",

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AU - Herrera, G.

AU - Gilman, R. H.

AU - Tsang, V. C.W.

AU - Pilcher, J. B.

AU - Diaz, J. F.

AU - Candy, E. J.

AU - Miranda, E.

AU - Naranjo, J.

AU - Torres, P.

AU - Gallo, C.

AU - Careamo, C.

AU - Verastegui, M.

AU - Montenegro, T.

AU - Alvarez, M.

AU - Evans, C.

AU - Gonzales, A. E.

AU - Castro, M.

AU - Guerron, A.

PY - 1994

Y1 - 1994

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Discrepancies between cerebral computed tomography and western blot in the diagnosis of neurocysticercosis

Abstract

ASJC Scopus subject areas

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