Discovery and optimization of pyrimidone indoline amide PI3Kβ inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers

Victor Certal, Jean Christophe Carry, Frank Halley, Angela Virone-Oddos, Fabienne Thompson, Bruno Filoche-Rommé, Youssef El-Ahmad, Andreas Karlsson, Véronique Charrier, Cécile Delorme, Alexey Rak, Pierre Yves Abecassis, Céline Amara, Loïc Vincent, Hélène Bonnevaux, Jean Paul Nicolas, Magali Mathieu, Thomas Bertrand, Jean Pierre Marquette, Nadine MichotTsiala Benard, Marc Antoine Perrin, Olivier Lemaitre, Stephane Guerif, Sébastien Perron, Sylvie Monget, Florence Gruss-Leleu, Gilles Doerflinger, Houlfa Guizani, Maurice Brollo, Laurence Delbarre, Luc Bertin, Patrick Richepin, Véronique Loyau, Carlos Garcia-Echeverria, Christoph Lengauer, Laurent Schio

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