DISC1 Partners with GSK3β in Neurogenesis

Guo li Ming; Hongjun Song

doi:10.1016/j.cell.2009.03.005

DISC1 Partners with GSK3β in Neurogenesis

Guo li Ming, Hongjun Song

School of Medicine

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

The protein DISC1, encoded by a gene implicated in schizophrenia susceptibility, regulates the development of postmitotic neurons. Mao et al. (2009) now report that DISC1 also regulates the proliferation of embryonic and adult neural progenitor cells through the GSK3β/β-catenin pathway, providing new insights into how susceptibility genes may contribute to the etiology of psychiatric disorders.

Original language	English (US)
Pages (from-to)	990-992
Number of pages	3
Journal	Cell
Volume	136
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2009.03.005
State	Published - Mar 20 2009

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.cell.2009.03.005

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title = "DISC1 Partners with GSK3β in Neurogenesis",

abstract = "The protein DISC1, encoded by a gene implicated in schizophrenia susceptibility, regulates the development of postmitotic neurons. Mao et al. (2009) now report that DISC1 also regulates the proliferation of embryonic and adult neural progenitor cells through the GSK3β/β-catenin pathway, providing new insights into how susceptibility genes may contribute to the etiology of psychiatric disorders.",

author = "Ming, {Guo li} and Hongjun Song",

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AB - The protein DISC1, encoded by a gene implicated in schizophrenia susceptibility, regulates the development of postmitotic neurons. Mao et al. (2009) now report that DISC1 also regulates the proliferation of embryonic and adult neural progenitor cells through the GSK3β/β-catenin pathway, providing new insights into how susceptibility genes may contribute to the etiology of psychiatric disorders.

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VL - 136

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JO - Cell

JF - Cell

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DISC1 Partners with GSK3β in Neurogenesis

Abstract

ASJC Scopus subject areas

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