TY - JOUR
T1 - Direct determination of copper in urine by atomic absorption spectrophotometry
AU - Spector, Harvey
AU - Glusman, Sheldon
AU - Jatlow, Peter
AU - Seligson, David
N1 - Funding Information:
This work was supported in part by United States Public Health Service Graduate Training Grant Number 5 TOI GMoo696.
PY - 1971/1
Y1 - 1971/1
N2 - A method is studied for the direct determination of copper in acidified urine by atomic absorption spectrophotometry. This method has the requisite accuracy, sensitivity, and specificity for clinical use. Interference by protein, and ionic components is absent. Urine copper levels obtained by this method agree with those found by colorimetric analysis following ashing. The results obtained for normal urine copper excretions are comparable to those obtained by other published methods. The method was useful in determining copper levels in the normal and pathologic ranges.
AB - A method is studied for the direct determination of copper in acidified urine by atomic absorption spectrophotometry. This method has the requisite accuracy, sensitivity, and specificity for clinical use. Interference by protein, and ionic components is absent. Urine copper levels obtained by this method agree with those found by colorimetric analysis following ashing. The results obtained for normal urine copper excretions are comparable to those obtained by other published methods. The method was useful in determining copper levels in the normal and pathologic ranges.
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U2 - 10.1016/0009-8981(71)90355-X
DO - 10.1016/0009-8981(71)90355-X
M3 - Article
C2 - 5544062
AN - SCOPUS:0014977666
SN - 0009-8981
VL - 31
SP - 5
EP - 11
JO - Clinica Chimica Acta
JF - Clinica Chimica Acta
IS - 1
ER -