TY - JOUR
T1 - Difluorinated malonaldehyde derivatives as useful difluoromethylene- containing building blocks
AU - Tsukamoto, Takashi
AU - Kitazume, Tomouya
PY - 1992/12/1
Y1 - 1992/12/1
N2 - New CF2-containing building blocks, ethyl 3-ethoxy-2,2-difluoro- 3-hydroxy-propionate and -propioamide, were prepared via formylation of α,α-difluorinated Reformatsky reagents, and reacted with active methylene compounds, nitromethane or phosphonoacetate to afford α,α-difluoro-functionalized esters and amides.
AB - New CF2-containing building blocks, ethyl 3-ethoxy-2,2-difluoro- 3-hydroxy-propionate and -propioamide, were prepared via formylation of α,α-difluorinated Reformatsky reagents, and reacted with active methylene compounds, nitromethane or phosphonoacetate to afford α,α-difluoro-functionalized esters and amides.
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U2 - 10.1039/C39920000540
DO - 10.1039/C39920000540
M3 - Article
AN - SCOPUS:37049069791
SN - 0022-4936
SP - 540
EP - 541
JO - Journal of the Chemical Society, Chemical Communications
JF - Journal of the Chemical Society, Chemical Communications
IS - 7
ER -