Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy

R. Ito; Elias R. Melhem; S. Mori; F. S. Eichler; G. V. Raymond; H. W. Moser

doi:10.1212/WNL.56.4.544

Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy

R. Ito, Elias R. Melhem, S. Mori, F. S. Eichler, G. V. Raymond, H. W. Moser

School of Medicine

Research output: Contribution to journal › Article › peer-review

68 Scopus citations

Abstract

Brain diffusion tensor MRI of 11 boys with X-linked adrenoleukodystrophy was performed. The authors determined quantitative isotropic apparent diffusion coefficient (ADC_i) and fractional anisotropy (FA) values in the white matter. ADC_i and FA values in the affected white matter were significantly different from those in normal-appearing white matter. Zonal ADC_i and FA gradations, which might originate from well-established histopathologic zonal changes, existed within affected white matter.

Original language	English (US)
Pages (from-to)	544-547
Number of pages	4
Journal	Neurology
Volume	56
Issue number	4
DOIs	https://doi.org/10.1212/WNL.56.4.544
State	Published - Feb 27 2001

ASJC Scopus subject areas

Clinical Neurology

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AU - Raymond, G. V.

AU - Moser, H. W.

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AB - Brain diffusion tensor MRI of 11 boys with X-linked adrenoleukodystrophy was performed. The authors determined quantitative isotropic apparent diffusion coefficient (ADCi) and fractional anisotropy (FA) values in the white matter. ADCi and FA values in the affected white matter were significantly different from those in normal-appearing white matter. Zonal ADCi and FA gradations, which might originate from well-established histopathologic zonal changes, existed within affected white matter.

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Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy

Abstract

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