Diffuse Parenchymal Lung Disease in Later Childhood

Lauren E. Bradford, Eveline Y. Wu, Frederic B. Askin, Timothy J. Vece

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Diffuse lung disease (DLD) refers to a heterogenous group of diseases that result in disordered gas exchange. The etiology of DLD in children aged 2–18years old is broad and is most frequently secondary to infectious or post-infectious processes, systemic disease, or immune dysfunction. Advances in genetic testing and imaging have led to improved diagnostic capabilities and earlier treatment. Treatment regimens have advanced as well, with newer targeted therapies. Given the rarity of these conditions, however, more research is needed to better understand disease pathology and optimize treatment.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Respiratory Medicine, Second Edition
PublisherElsevier
Pages244-262
Number of pages19
Volume6
ISBN (Electronic)9780081027240
ISBN (Print)9780081027233
DOIs
StatePublished - Jan 1 2021
Externally publishedYes

Keywords

  • Bronchiolitis obliterans
  • Children’s interstitial lung disease
  • Diffuse lung disease
  • Hypoxemia
  • Immune-related lung disease
  • Immunodeficiency
  • Interstitial lung disease
  • Pulmonary hemorrhage
  • Pulmonary vasculitis
  • Rheumatologic lung disease

ASJC Scopus subject areas

  • General Medicine

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