TY - JOUR
T1 - Dietary patterns and the risk of non-Hodgkin lymphoma
T2 - The multiethnic cohort
AU - Erber, Eva
AU - Maskarinec, Gertraud
AU - Gill, Jasmeet K.
AU - Park, Song Yi
AU - Kolonel, Laurence N.
N1 - Funding Information:
Declaration of interest: The MEC was supported by the National Cancer Institute (R37 CA54281). JG was supported by a postdoctoral fellowship (R25 CA 90956). The Hawaii Tumor Registry is supported by the SEER contract N01-PC-35137. The authors alone are responsible for the content and writing of the paper.
PY - 2009
Y1 - 2009
N2 - We examined dietary patterns and the risk of non-Hodgkin lymphoma (NHL) in the Multiethnic Cohort, which includes more than 215,000 Caucasians, African-Americans, Japanese-Americans, Native Hawaiians, and Latinos aged 45-75 at baseline. All subjects completed a validated food-frequency questionnaire. After a median follow-up time of 10 years, we identified 939 incident NHL cases through linkages with tumor registries. Three patterns, "Vegetables, ""Fruit and Milk," and "Fat and Meat," were analyzed using Cox regression. None of the patterns was significantly associated with the risk of NHL in the total population. However, the Vegetables pattern was inversely related to risk in Caucasian women with a hazard ratio of 0.56 (P trend = 0.04), and the Fat and Meat pattern was associated with a fivefold higher risk of follicular lymphoma in men (Ptrend = 0.03). The lack of significant results in men and women indicates a limited role of diet in NHL etiology, but dietary patterns might have ethnic- and subgroup-specific effects on NHL.
AB - We examined dietary patterns and the risk of non-Hodgkin lymphoma (NHL) in the Multiethnic Cohort, which includes more than 215,000 Caucasians, African-Americans, Japanese-Americans, Native Hawaiians, and Latinos aged 45-75 at baseline. All subjects completed a validated food-frequency questionnaire. After a median follow-up time of 10 years, we identified 939 incident NHL cases through linkages with tumor registries. Three patterns, "Vegetables, ""Fruit and Milk," and "Fat and Meat," were analyzed using Cox regression. None of the patterns was significantly associated with the risk of NHL in the total population. However, the Vegetables pattern was inversely related to risk in Caucasian women with a hazard ratio of 0.56 (P trend = 0.04), and the Fat and Meat pattern was associated with a fivefold higher risk of follicular lymphoma in men (Ptrend = 0.03). The lack of significant results in men and women indicates a limited role of diet in NHL etiology, but dietary patterns might have ethnic- and subgroup-specific effects on NHL.
KW - Non-Hodgkin lymphoma
KW - dietary patterns
KW - ethnicity
KW - prospective studies
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U2 - 10.1080/10428190903030841
DO - 10.1080/10428190903030841
M3 - Article
C2 - 19811330
AN - SCOPUS:77649325794
SN - 1042-8194
VL - 50
SP - 1269
EP - 1275
JO - Leukemia and Lymphoma
JF - Leukemia and Lymphoma
IS - 8
ER -