Diagnosis and management of the Budd-Chiari syndrome

Andrew S. Klein, John L. Cameron

Research output: Contribution to journalArticlepeer-review

61 Scopus citations


Occlusion or obstruction of hepatic venous outflow results in the Budd-Chiari syndrome. The disorder should be suspected in any patient who suddenly develops massive ascites, and the diagnosis can be confirmed quickly and accurately by hepatic venography. In the absence of surgical intervention, survival is rare. Inferior venacavography and percutaneous liver biopsy can be performed safely in these patients, and both procedures provide useful information for the selection of appropriate surgical therapy. Most cases of the Budd-Chiari syndrome are amenable to mesocaval or mesoatrial shunting. Those patients with documented cirrhosis or fulminant hepatic failure are best managed by orthotopic liver transplantation.

Original languageEnglish (US)
Pages (from-to)128-133
Number of pages6
JournalThe American Journal of Surgery
Issue number1
StatePublished - Jul 1990
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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