Diagnosis and characterization of brain tumors: MR spectroscopic imaging

Peter B. Barker

doi:10.1007/978-1-4419-5858-7_3

Diagnosis and characterization of brain tumors: MR spectroscopic imaging

Peter B. Barker

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Scopus citations

Abstract

In vivo proton magnetic resonance spectroscopy (MRS) was first demonstrated to be feasible in vivo in the human brain in the mid-1980s [1], and the first example of it being applied to human brain tumors following soon after in 1989 [2]. It was already apparent from this paper that brain tumors had greatly different metabolite profiles compared to normal tissue, and that differences in spectra may exist between different brain lesions of different pathologies. Since that time, there has been steady progress in the use of MRS and the related technique of magnetic resonance spectroscopic imaging (MRSI) for the clinical evaluation of human brain tumors [3].

Original language	English (US)
Title of host publication	Functional Brain Tumor Imaging
Publisher	Springer New York
Pages	39-55
Number of pages	17
Volume	9781441958587
ISBN (Electronic)	9781441958587
ISBN (Print)	1441958576, 9781441958570
DOIs	https://doi.org/10.1007/978-1-4419-5858-7_3
State	Published - May 1 2013

ASJC Scopus subject areas

General Medicine
General Biochemistry, Genetics and Molecular Biology

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AB - In vivo proton magnetic resonance spectroscopy (MRS) was first demonstrated to be feasible in vivo in the human brain in the mid-1980s [1], and the first example of it being applied to human brain tumors following soon after in 1989 [2]. It was already apparent from this paper that brain tumors had greatly different metabolite profiles compared to normal tissue, and that differences in spectra may exist between different brain lesions of different pathologies. Since that time, there has been steady progress in the use of MRS and the related technique of magnetic resonance spectroscopic imaging (MRSI) for the clinical evaluation of human brain tumors [3].

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Diagnosis and characterization of brain tumors: MR spectroscopic imaging

Abstract

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