TY - JOUR
T1 - Developmental and environmental influences on physiology and behavior - 2014 Alan N. Epstein Research Award
AU - Tamashiro, Kellie L.K.
N1 - Funding Information:
As with any challenging journey there are bound to be periods when you ask yourself, “why am I doing this and is it really worth it?” I certainly did, many times. My answer was, obviously, yes and it is because of the great people I worked with in the lab, my mentors who provided support, guidance, and many words of wisdom just when I needed it, and the many colleagues I knew I could count on for help and advice. I share this award with so many people who have supported me along this journey. Many thanks to my family who provided unconditional love and support, even though I chose the road less traveled and moved further east and away from Hawaii with every step of my career. I could not have navigated the path without the guidance and support of many mentors along the way, in particular, Bob & Caroline Blanchard, Ryuzo Yanagimachi, Randall Sakai, and Tim Moran. I thank the individuals who nominated me and provided letters of support for me for the Epstein Award. I extend heartfelt gratitude to the Epstein family for generously endowing the Alan N. Epstein Research Award to recognize early career investigators in this field and to keep Alan's legacy alive ( Fig. 4 ). I have a deep appreciation for the SSIB membership who, for the last 14 years, provided me with an environment that is collegial and nurturing, but scientifically critical and challenging for SSIB-lings like myself to learn, grow, and mature in. Finally, thank you to the funding agencies who provided financial support for these and other studies: NIH NIDDK ( T32DK-59803 ; R01DK066596 and R01DK068273 to R.R.S.; R01DK077623 to T.H.M.), NINDS ( F31NS047791 ), NIMH ( T32MH-15330 ), NICHD ( K99/R00HD055030 ), NIMH ( R21MH097150 ), the Albert J. Ryan Foundation , the Brain and Behavior Research Foundation (NARSAD Young Investigator Award) , and the Maryland Nutrition and Obesity Research Center (P30 DK072488) .
Funding Information:
As a new post doc, one of my first priorities was to secure my own funding so I started collecting data for an NIH F32 post-doc fellowship proposal. Then one Sunday morning a few months after I started in the lab, a story in the Baltimore Sun. newspaper caught my eye. It described a brand new funding initiative issued by the NIH that was aimed at helping facilitate post doctoral trainees' transition from fellow to independent investigator, the K99/R00 Pathway to Independence Award (a.k.a. “kangaroo” award). I was one of the first awardees of the K99/R00 award which is what helped to kick start my post-doctoral research and set the foundation for my current program of research. I learned that opportunities can present themselves in the most unexpected places and that being ready to capitalize on them, and actually pursuing them, at any time is essential.
Publisher Copyright:
© 2015 Elsevier Inc.
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Environmental factors acting during development of an individual may influence future health and disease susceptibility. Stressors, including altered diet, psychosocial stress, and immune challenge, during gestation can have negative consequences on the intrauterine environment and increase disease susceptibility of the developing fetus. The long-term effects on offspring have been observed in humans and include greater susceptibility to psychiatric disease, such as depression and anxiety disorders, and adverse metabolic conditions including obesity, diabetes and cardiovascular disease. Studies in my laboratory use rodent models and incorporate a multilevel approach to determine the behavioral, physiological, and neurobiological correlates of disease development as a consequence of early life stressors. The road I took in developing this research program was a rather circuitous one and navigating that path would not have been possible without the many mentors, colleagues, fellows and students who provided critical support. Although my name appears on the plaque of the Alan N. Epstein Research Award, I share this with all those I had the privilege of working with along that road, as briefly summarized in this article.
AB - Environmental factors acting during development of an individual may influence future health and disease susceptibility. Stressors, including altered diet, psychosocial stress, and immune challenge, during gestation can have negative consequences on the intrauterine environment and increase disease susceptibility of the developing fetus. The long-term effects on offspring have been observed in humans and include greater susceptibility to psychiatric disease, such as depression and anxiety disorders, and adverse metabolic conditions including obesity, diabetes and cardiovascular disease. Studies in my laboratory use rodent models and incorporate a multilevel approach to determine the behavioral, physiological, and neurobiological correlates of disease development as a consequence of early life stressors. The road I took in developing this research program was a rather circuitous one and navigating that path would not have been possible without the many mentors, colleagues, fellows and students who provided critical support. Although my name appears on the plaque of the Alan N. Epstein Research Award, I share this with all those I had the privilege of working with along that road, as briefly summarized in this article.
KW - Assisted reproductive techniques
KW - Developmental origins of health and disease
KW - Maternal diet
KW - Maternal stress
KW - Social stress
KW - Somatic cell nuclear transfer
UR - http://www.scopus.com/inward/record.url?scp=84961151050&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84961151050&partnerID=8YFLogxK
U2 - 10.1016/j.physbeh.2015.08.019
DO - 10.1016/j.physbeh.2015.08.019
M3 - Review article
C2 - 26291266
AN - SCOPUS:84961151050
SN - 0031-9384
VL - 152
SP - 508
EP - 515
JO - Physiology and Behavior
JF - Physiology and Behavior
ER -