Development of new immunologic approaches to cancer therapy

Steven A. Rosenberg

doi:10.1159/000169486

Development of new immunologic approaches to cancer therapy

Steven A. Rosenberg

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

New approaches to the immunotherapy of cancer have been developed based on the adoptive transfer of activated lymphoid cells in conjunction with interleukin-2. This approach is successful in mediating the regression of established pulmonary and hepatic metastases in experimental animal models. The results of preliminary clinical trials in patients with advanced cancer have shown that this treatment approach is capable of mediating regression of cancer in humans as well.

Original language	English (US)
Pages (from-to)	69-76
Number of pages	8
Journal	Blood Purification
Volume	6
Issue number	2
DOIs	https://doi.org/10.1159/000169486
State	Published - 1988
Externally published	Yes

Keywords

Adoptive therapy
Cancer
Immunotherapy
Interleukin-2

ASJC Scopus subject areas

Hematology
Nephrology

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10.1159/000169486

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title = "Development of new immunologic approaches to cancer therapy",

abstract = "New approaches to the immunotherapy of cancer have been developed based on the adoptive transfer of activated lymphoid cells in conjunction with interleukin-2. This approach is successful in mediating the regression of established pulmonary and hepatic metastases in experimental animal models. The results of preliminary clinical trials in patients with advanced cancer have shown that this treatment approach is capable of mediating regression of cancer in humans as well.",

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year = "1988",

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language = "English (US)",

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T1 - Development of new immunologic approaches to cancer therapy

AU - Rosenberg, Steven A.

PY - 1988

Y1 - 1988

N2 - New approaches to the immunotherapy of cancer have been developed based on the adoptive transfer of activated lymphoid cells in conjunction with interleukin-2. This approach is successful in mediating the regression of established pulmonary and hepatic metastases in experimental animal models. The results of preliminary clinical trials in patients with advanced cancer have shown that this treatment approach is capable of mediating regression of cancer in humans as well.

AB - New approaches to the immunotherapy of cancer have been developed based on the adoptive transfer of activated lymphoid cells in conjunction with interleukin-2. This approach is successful in mediating the regression of established pulmonary and hepatic metastases in experimental animal models. The results of preliminary clinical trials in patients with advanced cancer have shown that this treatment approach is capable of mediating regression of cancer in humans as well.

KW - Adoptive therapy

KW - Cancer

KW - Immunotherapy

KW - Interleukin-2

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UR - http://www.scopus.com/inward/citedby.url?scp=0023894826&partnerID=8YFLogxK

U2 - 10.1159/000169486

DO - 10.1159/000169486

M3 - Review article

C2 - 3293619

AN - SCOPUS:0023894826

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VL - 6

SP - 69

EP - 76

JO - Blood Purification

JF - Blood Purification

IS - 2

ER -

Development of new immunologic approaches to cancer therapy

Abstract

Keywords

ASJC Scopus subject areas

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