TY - JOUR
T1 - Development of human mast cells from their progenitors
AU - Ishizaka, Teruko
AU - Mitsui, Hideki
AU - Yanagida, Makoto
AU - Miura, Toru
AU - Dvorak, A. M.
N1 - Funding Information:
The authors express their special gratitude to Drs Anne-Marie A Irdni and Lawrence 1) Schwartz, Medical College of Virginia, Virginia Commonwealth University, Richmond, ViiInia for their collaboration and contribution. This is publication number 85 from La Jolla Institute for Allergy and Immunology, supported by Health and Human Service grants AI-loo60 and AI-33372, and a research contract with Gemini Science, Inc.
Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1993/12
Y1 - 1993/12
N2 - Two types of human mast cells, which are morphologically similar to skin mast cells and lung mast cells, repectively, can be developed from pluripotent stem cells under different culture conditions. The major growth factor for mast-cell development is c-kit ligand, which induces mastocytosis in vivo. However, this cytokine is not sufficient for full maturation of the cells.
AB - Two types of human mast cells, which are morphologically similar to skin mast cells and lung mast cells, repectively, can be developed from pluripotent stem cells under different culture conditions. The major growth factor for mast-cell development is c-kit ligand, which induces mastocytosis in vivo. However, this cytokine is not sufficient for full maturation of the cells.
UR - http://www.scopus.com/inward/record.url?scp=0027425322&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0027425322&partnerID=8YFLogxK
U2 - 10.1016/0952-7915(93)90109-6
DO - 10.1016/0952-7915(93)90109-6
M3 - Article
C2 - 8297527
AN - SCOPUS:0027425322
SN - 0952-7915
VL - 5
SP - 937
EP - 943
JO - Current Opinion in Immunology
JF - Current Opinion in Immunology
IS - 6
ER -