TY - JOUR
T1 - Development of flexible multi-channel muscle interfaces with advanced sensing function
AU - Wang, Jiahui
AU - Xiang, Zhuolin
AU - Gammad, Gil Gerald Lasam
AU - Thakor, Nitish V.
AU - Yen, Shih Cheng
AU - Lee, Chengkuo
N1 - Funding Information:
This work was supported by grants from the National Research Foundation (NRF) CRP project “Self-Powered Body Sensor Network for Disease Management and Prevention Oriented Healthcare (NRF2011 NRF-CRP001-057)” (R-263-000-A27-281) and National Research Foundation (NRF) CRP project “Peripheral Nerve Prostheses: A Paradigm Shift in Restoring Dexterous Limb Function (NRF-CRP10-2012-01)” (R-719-000-001-281).
Publisher Copyright:
© 2016 Elsevier B.V.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2016/10/1
Y1 - 2016/10/1
N2 - Functional Electrical Stimulation (FES) helps individuals with paralysis recover their muscle function. As opposed to voluntary muscle movement, which involves probabilistic recruitment of different muscle fibers at the neuromuscular junction, FES is usually performed using electrodes with just one channel, and as a result, tends to stimulate the same muscle fibers repeatedly. This induces excess muscle fatigue, which manifests itself as a loss of generated force after extended stimulation. Since the force generated is not typically measured in a FES system, electrical stimulation parameters need to be adjusted manually when muscle fatigue occurs. To address the problems of current FES, we propose a flexible muscle interface device with multiple stimulation electrodes and an integrated pH sensor. By using different subsets of electrodes for stimulation, alternating excitation of muscle fibers can be achieved to reduce fatigue in the muscles. At the same time, the pH sensor helps to provide quantified information about the state of the muscles, potentially allowing the stimulation parameters to be altered in a closed-loop fashion. Different interfacing materials were compared in terms of impedance and charge delivery ability. IrOx exhibited lower impedance of 0.7 kΩ at 1 kHz, and higher charge storage capacity (CSC) of 23.77 mC/cm2. In in vivo muscle stimulation experiments, the use of alternating electrodes during stimulation induced less muscle fatigue, as well as less pH change, compared to using fixed electrode pairs. This flexible multi-channel stimulation device can potentially be used to reduce and monitor muscle fatigue during functional electrical stimulation.
AB - Functional Electrical Stimulation (FES) helps individuals with paralysis recover their muscle function. As opposed to voluntary muscle movement, which involves probabilistic recruitment of different muscle fibers at the neuromuscular junction, FES is usually performed using electrodes with just one channel, and as a result, tends to stimulate the same muscle fibers repeatedly. This induces excess muscle fatigue, which manifests itself as a loss of generated force after extended stimulation. Since the force generated is not typically measured in a FES system, electrical stimulation parameters need to be adjusted manually when muscle fatigue occurs. To address the problems of current FES, we propose a flexible muscle interface device with multiple stimulation electrodes and an integrated pH sensor. By using different subsets of electrodes for stimulation, alternating excitation of muscle fibers can be achieved to reduce fatigue in the muscles. At the same time, the pH sensor helps to provide quantified information about the state of the muscles, potentially allowing the stimulation parameters to be altered in a closed-loop fashion. Different interfacing materials were compared in terms of impedance and charge delivery ability. IrOx exhibited lower impedance of 0.7 kΩ at 1 kHz, and higher charge storage capacity (CSC) of 23.77 mC/cm2. In in vivo muscle stimulation experiments, the use of alternating electrodes during stimulation induced less muscle fatigue, as well as less pH change, compared to using fixed electrode pairs. This flexible multi-channel stimulation device can potentially be used to reduce and monitor muscle fatigue during functional electrical stimulation.
KW - Electrical stimulation
KW - Flexible
KW - Multi-channel
KW - Muscle fatigue
KW - Muscle interface
KW - pH monitoring
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U2 - 10.1016/j.sna.2016.07.034
DO - 10.1016/j.sna.2016.07.034
M3 - Article
AN - SCOPUS:84986563781
SN - 0924-4247
VL - 249
SP - 269
EP - 275
JO - Sensors and Actuators, A: Physical
JF - Sensors and Actuators, A: Physical
ER -