Development of canine benign prostatic hyperplasia with age

Stephen J. Berry, John D. Strandberg, Donald S. Coffey, William J. Saunders

Research output: Contribution to journalArticlepeer-review

100 Scopus citations


The prevalence and growth of benign prostatic hyperplasia (BPH) in beagles as a function of age were studied. The normal prostate gland was 12 ± 3 gm in beagles 2.1‐3.0 years of age; this weight remained unchanged unless BPH developed. Histologic evidence of BPH developed at an early age with a prevalence of 16% of the dogs by the age 2 years. Fifty percent of the dogs had BPH, determined histopathologically by age 4.1‐5.0 years. The average weight of the prostate gland remained constant until after age 8 years. With age, the pathologic features of BPH changed from glandular to the complex form, with no increase in prostate weight until after 8 years. Reinitiation of growth occurred and prostate weight increased to greater than 36 gm in eight of 185 beagles older than age 8 years.

Original languageEnglish (US)
Pages (from-to)363-373
Number of pages11
JournalThe Prostate
Issue number4
StatePublished - 1986
Externally publishedYes


  • BPH
  • aging
  • canine
  • complex
  • development
  • glandular
  • normal
  • prostate

ASJC Scopus subject areas

  • Oncology
  • Urology


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