Development of a specific live-cell assay for native autophagic flux

Keyphrases

• Autophagy 100%
• Autophagic Flux 100%
• Autophagy Pathway 100%
• Live Detection 100%
• Amyotrophic Lateral Sclerosis 66%
• Dendra2 66%
• Amyotrophic Lateral Sclerosis/frontotemporal Dementia 66%
• RNA-binding Protein 33%
• Cellular Proteins 33%
• Therapeutic Potential 33%
• Living Cells 33%
• Human Cells 33%
• Disease Model 33%
• Frontotemporal Dementia 33%
• Mutant Forms 33%
• Dementia Subtypes 33%
• Chemical Library 33%
• Neuronal Model 33%
• Conserved Pathways 33%
• TAR DNA-binding Protein 43 (TDP-43) 33%
• Automated Microscopy 33%
• C9orf72 33%
• UBQLN2 33%
• Cas9 Protein 33%
• Autophagic Activity 33%
• MAP1LC3B 33%
• High-throughput Drug Screen 33%
• Photoswitchable Molecules 33%
• Autophagy Dysfunction 33%
• Autophagy Modulators 33%
• Optical Pulse Labeling 33%
• Evolutionarily Conserved 33%
• Cellular Organelles 33%
• Human Motor Neuron 33%
• Clinically Relevant Drugs 33%
• CRISPR-Cas9 Genome Editing 33%

Biochemistry, Genetics and Molecular Biology

• Autophagy 100%
• Cell Assay 100%
• CRISPR/Cas9 22%
• RNA-binding Protein 11%
• Motor Neuron 11%
• Pulse Labelling 11%
• Genome Editing 11%
• TAR DNA Binding Protein 11%
• UBQLN2 11%
• Deficiency 11%