Abstract
A multi-modal sensor has been developed for non-invasive, real time, in vivo monitoring of oxygen intake, consumption and blood flow dynamics in tumor tissue during ischemia-reperfusion. The sensor head integrated a near infrared tissue oximeter for tissue oxygen saturation and hemoglobin concentration measurement, a laser Doppler for blood flow measurement, and an electron paramagnetic resonance spectroscope (EPRS) for oxygen tension measurement. The sensor has been tested on athymic NU/NU mice with xenograft pancreatic cancer implanted on right legs. Ischemia-reperfusion was introduced by physical ligation of the femur artery. Preliminary results demonstrated technical feasibility of simultaneous tissue oxygen and blood flow measurements. Further data analysis is on the way.
| Original language | English (US) |
|---|---|
| Title of host publication | IRMMW-THz 2006 - 31st International Conference on Infrared and Millimeter Waves and 14th International Conference on Terahertz Electronics |
| Pages | 249 |
| Number of pages | 1 |
| DOIs | |
| State | Published - 2006 |
| Externally published | Yes |
| Event | IRMMW-THz 2006 - 31st International Conference on Infrared and Millimeter Waves and 14th International Conference on Terahertz Electronics - Shanghai, China Duration: Sep 18 2006 → Sep 22 2006 |
Other
| Other | IRMMW-THz 2006 - 31st International Conference on Infrared and Millimeter Waves and 14th International Conference on Terahertz Electronics |
|---|---|
| Country/Territory | China |
| City | Shanghai |
| Period | 9/18/06 → 9/22/06 |
ASJC Scopus subject areas
- Computer Networks and Communications
- Electrical and Electronic Engineering