Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy

Chen Wang; Chenxuan Wang; Xiaobo Mao; Aihua Yang; Lin Niu; Shengnan Wang; Denghua Li; Yuanyuan Guo; Yibing Wang; Yanlian Yang

doi:10.1039/c1cc12380g

Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy

Chen Wang, Chenxuan Wang, Xiaobo Mao, Aihua Yang, Lin Niu, Shengnan Wang, Denghua Li, Yuanyuan Guo, Yibing Wang, Yanlian Yang

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The binding behaviour of labeling molecule copper phthalocyanine tetrasulfonate sodium (PcCu(SO₃Na)₄) on the assemblies of representative polyamino acids has been studied by using scanning tunneling microscopy (STM). By directly visualizing the adsorption and distribution of the labeling species on the peptide assemblies in STM images, one could obtain relative binding affinities of the labeling molecule with different amino acid residues.

Original language	English (US)
Pages (from-to)	10638-10640
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	38
DOIs	https://doi.org/10.1039/c1cc12380g
State	Published - Oct 14 2011
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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abstract = "The binding behaviour of labeling molecule copper phthalocyanine tetrasulfonate sodium (PcCu(SO3Na)4) on the assemblies of representative polyamino acids has been studied by using scanning tunneling microscopy (STM). By directly visualizing the adsorption and distribution of the labeling species on the peptide assemblies in STM images, one could obtain relative binding affinities of the labeling molecule with different amino acid residues.",

author = "Chen Wang and Chenxuan Wang and Xiaobo Mao and Aihua Yang and Lin Niu and Shengnan Wang and Denghua Li and Yuanyuan Guo and Yibing Wang and Yanlian Yang",

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T1 - Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy

AU - Wang, Chen

AU - Wang, Chenxuan

AU - Mao, Xiaobo

AU - Yang, Aihua

AU - Niu, Lin

AU - Wang, Shengnan

AU - Li, Denghua

AU - Guo, Yuanyuan

AU - Wang, Yibing

AU - Yang, Yanlian

PY - 2011/10/14

Y1 - 2011/10/14

N2 - The binding behaviour of labeling molecule copper phthalocyanine tetrasulfonate sodium (PcCu(SO3Na)4) on the assemblies of representative polyamino acids has been studied by using scanning tunneling microscopy (STM). By directly visualizing the adsorption and distribution of the labeling species on the peptide assemblies in STM images, one could obtain relative binding affinities of the labeling molecule with different amino acid residues.

AB - The binding behaviour of labeling molecule copper phthalocyanine tetrasulfonate sodium (PcCu(SO3Na)4) on the assemblies of representative polyamino acids has been studied by using scanning tunneling microscopy (STM). By directly visualizing the adsorption and distribution of the labeling species on the peptide assemblies in STM images, one could obtain relative binding affinities of the labeling molecule with different amino acid residues.

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EP - 10640

JO - Chemical Communications

JF - Chemical Communications

IS - 38

ER -

Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy

Abstract

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