Detection of type-specific antibodies to HSV-1 and HSV-2: Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA

Amelia W. Maters; Christina V. Wright; Maria Teresa Lee; Greta Schwichtenberg; Barbara Detrick

doi:10.1016/j.diagmicrobio.2012.03.023

Detection of type-specific antibodies to HSV-1 and HSV-2: Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA

Amelia W. Maters, Christina V. Wright, Maria Teresa Lee, Greta Schwichtenberg, Barbara Detrick

School of Medicine

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON® HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6% (HSV-1) and 100% (HSV-2). The LIAISON® methodology has several advantages.

Original language	English (US)
Pages (from-to)	273-274
Number of pages	2
Journal	Diagnostic Microbiology and Infectious Disease
Volume	73
Issue number	3
DOIs	https://doi.org/10.1016/j.diagmicrobio.2012.03.023
State	Published - Jul 2012

Keywords

Chemiluminescence
ELISA
HSV-1
HSV-2
Serology

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.diagmicrobio.2012.03.023

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title = "Detection of type-specific antibodies to HSV-1 and HSV-2: Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA",

abstract = "Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON{\textregistered} HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6% (HSV-1) and 100% (HSV-2). The LIAISON{\textregistered} methodology has several advantages.",

keywords = "Chemiluminescence, ELISA, HSV-1, HSV-2, Serology",

author = "Maters, {Amelia W.} and Wright, {Christina V.} and Lee, {Maria Teresa} and Greta Schwichtenberg and Barbara Detrick",

note = "Funding Information: This study was supported, in part, by a grant from DiaSorin . ",

year = "2012",

month = jul,

doi = "10.1016/j.diagmicrobio.2012.03.023",

language = "English (US)",

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journal = "Diagnostic Microbiology and Infectious Disease",

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T1 - Detection of type-specific antibodies to HSV-1 and HSV-2

T2 - Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA

AU - Maters, Amelia W.

AU - Wright, Christina V.

AU - Lee, Maria Teresa

AU - Schwichtenberg, Greta

AU - Detrick, Barbara

N1 - Funding Information: This study was supported, in part, by a grant from DiaSorin .

PY - 2012/7

Y1 - 2012/7

N2 - Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON® HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6% (HSV-1) and 100% (HSV-2). The LIAISON® methodology has several advantages.

AB - Type-specific serologic tests for human herpes simplex virus (HSV) are critically important for sexually transmitted disease evaluation. We compared the LIAISON® HSV-1 and HSV-2 Type Specific assays relative to an established commercial ELISA. The overall agreement of the chemiluminescence immunoassay versus the ELISA assay was 99.6% (HSV-1) and 100% (HSV-2). The LIAISON® methodology has several advantages.

KW - Chemiluminescence

KW - ELISA

KW - HSV-1

KW - HSV-2

KW - Serology

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M3 - Article

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AN - SCOPUS:84862165135

SN - 0732-8893

VL - 73

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EP - 274

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 3

ER -

Detection of type-specific antibodies to HSV-1 and HSV-2: Comparative analysis of a chemiluminescence immunoassay with a conventional ELISA

Abstract

Keywords

ASJC Scopus subject areas

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