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DETECTION OF THE SARS-COV-2 SPIKE PROTEIN IN SALIVA WITH SHRINKY-DINK© ELECTRODES

  • Julia A. Zakashansky
  • , Amanda H. Imamura
  • , Darwin F. Salgado
  • , Heather C. Romero Mercieca
  • , Raphael F.L. Aguas
  • , Angelou M. Lao
  • , Joseph Pariser
  • , Netzahualcóyotl Arroyo-Currás
  • , Michelle Khine

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Our recently published1 investigation of an aptamer-based electrochemical (E-AB) assay that recognizes the spike protein of SARS-CoV-2 in saliva for viral infection detection yielded an exceptionally low limit of quantification of less than 0.001 fg mL-1 of the SARS-CoV-2 S1 subunit. Since this work, we have also been able to demonstrate detection of inactivated virus in saliva.

Original languageEnglish (US)
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages861-862
Number of pages2
ISBN (Electronic)9781733419031
StatePublished - 2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: Oct 10 2021Oct 14 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2110/14/21

Keywords

  • SARS-CoV-2
  • Shrinky-dink
  • antigen test
  • aptamers
  • electrochemical detection
  • square wave

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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