TY - GEN
T1 - Detection of schizophrenia using fMRI data via projection pursuit
AU - Demirci, Oguz
AU - Calhoun, Vince D.
PY - 2007/12/1
Y1 - 2007/12/1
N2 - Schizophrenia is currently diagnosed based upon symptoms and there is no quantitative, biologically based technique as yet. Classification of individuals into schizophrenia and control groups based on fMRI data is thus of great interest to support, psychiatric diagnoses. We applied a novel projection pursuit technique on the default mode component of 70 subjects' fMRI data obtained during an auditory odd-ball task. The validity of the technique was tested with a leave-one-out method and the detection performance varied between 80% and 90% applying different masks. The findings suggest that the proposed data reduction algorithm is effective in classifying individuals into schizophrenia and control groups and useful as a diagnostic tool.
AB - Schizophrenia is currently diagnosed based upon symptoms and there is no quantitative, biologically based technique as yet. Classification of individuals into schizophrenia and control groups based on fMRI data is thus of great interest to support, psychiatric diagnoses. We applied a novel projection pursuit technique on the default mode component of 70 subjects' fMRI data obtained during an auditory odd-ball task. The validity of the technique was tested with a leave-one-out method and the detection performance varied between 80% and 90% applying different masks. The findings suggest that the proposed data reduction algorithm is effective in classifying individuals into schizophrenia and control groups and useful as a diagnostic tool.
UR - https://www.scopus.com/pages/publications/48149085347
UR - https://www.scopus.com/pages/publications/48149085347#tab=citedBy
U2 - 10.1109/MLSP.2007.4414306
DO - 10.1109/MLSP.2007.4414306
M3 - Conference contribution
AN - SCOPUS:48149085347
SN - 1424415667
SN - 9781424415663
T3 - Machine Learning for Signal Processing 17 - Proceedings of the 2007 IEEE Signal Processing Society Workshop, MLSP
SP - 199
EP - 204
BT - Machine Learning for Signal Processing 17 - Proceedings of the 2007 IEEE Signal Processing Society Workshop, MLSP
T2 - 17th IEEE International Workshop on Machine Learning for Signal Processing, MLSP-2007
Y2 - 27 August 2007 through 29 August 2007
ER -