Detection of Reactive Oxygen and Nitrogen Species EPR Spin Trapping

Frederick A. Villamena, Jay L. Zweier

Research output: Contribution to journalArticlepeer-review

164 Scopus citations


Electron paramagnetic resonance spin trapping has become an indispensable tool for the specific detection of reactive oxygen free radicals in biological systems. In this review we describe some of the advantages as well as some experimental considerations of this technique and how it can be applied to biological systems to measure oxidative stress.

Original languageEnglish (US)
Pages (from-to)619-629
Number of pages11
JournalAntioxidants and Redox Signaling
Issue number3
StatePublished - Jun 2004
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry


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