Detection of Five Components Having Antibody Activity in Rat Antisera

Jay Banovitz, Kimishige Ishizaka

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


By radioimmunoelectrophoresis, antibodies associated with γ1, γ2 and γM globulins and 2 unidentified components, U1 and U2, were detected in rat antisera to BSA and BGG. When rats were immunized with these antigens adsorbed to bentonite or included in complete Freund's adjuvant, the sequence of the immune response in rats involves first the formation of γ1 antibody followed upon further immunization by γ2 antibody. Generally, γM and the unknown components, U1 and U2, only appeared in hyperimmune sera.

Original languageEnglish (US)
Pages (from-to)78-82
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Issue number1
StatePublished - May 1967

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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