Detection of filarial antigen in urine of humans with Wuchereria bancrofti infection by immunoradiometric assay

M. V.R. Reddy; B. C. Harinath; R. G. Hamilton

Detection of filarial antigen in urine of humans with Wuchereria bancrofti infection by immunoradiometric assay

M. V.R. Reddy, B. C. Harinath, R. G. Hamilton

Research output: Contribution to journal › Article › peer-review

Abstract

Human urine samples of different groups were analyzed for the presence of filarial antigen by immuno-radiometric assay (IRMA) using ¹²⁵I-Rabbit IgG antibodies to B. malayi antigen. Six out of ten microfilaraemia, one out of five clinical filariasis had detectable antigen, while none of the endemic and non-endemic normals (n=12) were positive. The effect of heat-acid treatment on the detectability of antigen in the urine and serum was explored. Heat-acid treatment in general did not reduce the level of filarial antigen in the urine samples while there was a measurable reduction in the antigen levels in the sera.

Original language	English (US)
Pages (from-to)	515-519
Number of pages	5
Journal	Indian journal of experimental biology
Volume	22
Issue number	10
State	Published - Dec 1 1984
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Molecular Biology
Cell Biology

Cite this

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title = "Detection of filarial antigen in urine of humans with Wuchereria bancrofti infection by immunoradiometric assay",

abstract = "Human urine samples of different groups were analyzed for the presence of filarial antigen by immuno-radiometric assay (IRMA) using 125I-Rabbit IgG antibodies to B. malayi antigen. Six out of ten microfilaraemia, one out of five clinical filariasis had detectable antigen, while none of the endemic and non-endemic normals (n=12) were positive. The effect of heat-acid treatment on the detectability of antigen in the urine and serum was explored. Heat-acid treatment in general did not reduce the level of filarial antigen in the urine samples while there was a measurable reduction in the antigen levels in the sera.",

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year = "1984",

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AU - Reddy, M. V.R.

AU - Harinath, B. C.

AU - Hamilton, R. G.

PY - 1984/12/1

Y1 - 1984/12/1

N2 - Human urine samples of different groups were analyzed for the presence of filarial antigen by immuno-radiometric assay (IRMA) using 125I-Rabbit IgG antibodies to B. malayi antigen. Six out of ten microfilaraemia, one out of five clinical filariasis had detectable antigen, while none of the endemic and non-endemic normals (n=12) were positive. The effect of heat-acid treatment on the detectability of antigen in the urine and serum was explored. Heat-acid treatment in general did not reduce the level of filarial antigen in the urine samples while there was a measurable reduction in the antigen levels in the sera.

AB - Human urine samples of different groups were analyzed for the presence of filarial antigen by immuno-radiometric assay (IRMA) using 125I-Rabbit IgG antibodies to B. malayi antigen. Six out of ten microfilaraemia, one out of five clinical filariasis had detectable antigen, while none of the endemic and non-endemic normals (n=12) were positive. The effect of heat-acid treatment on the detectability of antigen in the urine and serum was explored. Heat-acid treatment in general did not reduce the level of filarial antigen in the urine samples while there was a measurable reduction in the antigen levels in the sera.

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Detection of filarial antigen in urine of humans with Wuchereria bancrofti infection by immunoradiometric assay

Abstract

ASJC Scopus subject areas

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