Detection and genotyping of cervical HPV with simultaneous cervical cytology in Turkish women: A hospital-based study

Kunter Yuce, Ahmet Pinar, Mehmet Coskun Salman, Alpaslan Alp, Berkan Sayal, Selen Dogan, Gulsen Hascelik

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Purpose To investigate the prevalence of cervical human papilloma virus (HPV) with genotyping and simultaneous cervical cytology among Turkish women in a university hospital. A review of literature was done as well to summarize the results of similar Turkish studies based on hospital data. Methods Women who were subjected to cervical HPV-DNA testing with simultaneous cervical Pap test were included. Seeplex HPV 18-plex Genotyping Test was used for HPV detection and typing. Liquid-based cytology was used for Pap test and Bethesda system was used for results. Results Study group included 890 patients with a mean age of 39.5 years. The prevalence of any HPV was 25.7% while high-risk HPV was positive in 23.0%. There were no significant differences in HPV prevalence between younger and older women. Among HPV-positive women, 89.5% had at least one type of high-risk HPV. Most common HPV was type 16 followed by type 31 and 51. Abnormal cervical cytology rate was 11.6%. Rate of HPV positivity was significantly higher in women with abnormal cervical cytology compared to women with normal cytology (54.4 vs. 22.0%). Conclusions Cervical HPV infection is a serious and gradually growing problem for Turkish women according to hospital-based data. This may be associated with low age at marriage and more sensitive HPV detection methods.

Original languageEnglish (US)
Pages (from-to)203-208
Number of pages6
JournalArchives of Gynecology and Obstetrics
Issue number1
StatePublished - Jul 1 2012


  • Cervical cancer
  • Human papilloma virus
  • Pap smear
  • Turkey

ASJC Scopus subject areas

  • Obstetrics and Gynecology


Dive into the research topics of 'Detection and genotyping of cervical HPV with simultaneous cervical cytology in Turkish women: A hospital-based study'. Together they form a unique fingerprint.

Cite this