TY - JOUR
T1 - Detection and Characterization of Musculoskeletal Cancer Using Whole-Body Magnetic Resonance Imaging
AU - Isaac, Amanda
AU - Lecouvet, Frederic
AU - Dalili, Danoob
AU - Fayad, Laura
AU - Pasoglou, Vasiliki
AU - Papakonstantinou, Olympia
AU - Ahlawat, Shivani
AU - Messiou, Christina
AU - Weber, Marc André
AU - Padhani, Anwar R.
N1 - Publisher Copyright:
© 2020 BMJ Publishing Group. All rights reserved.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Whole-body magnetic resonance imaging (WB-MRI) is gradually being integrated into clinical pathways for the detection, characterization, and staging of malignant tumors including those arising in the musculoskeletal (MSK) system. Although further developments and research are needed, it is now recognized that WB-MRI enables reliable, sensitive, and specific detection and quantification of disease burden, with clinical applications for a variety of disease types and a particular application for skeletal involvement. Advances in imaging techniques now allow the reliable incorporation of WB-MRI into clinical pathways, and guidelines recommending its use are emerging. This review assesses the benefits, clinical applications, limitations, and future capabilities of WB-MRI in the context of other next-generation imaging modalities, as a qualitative and quantitative tool for the detection and characterization of skeletal and soft tissue MSK malignancies.
AB - Whole-body magnetic resonance imaging (WB-MRI) is gradually being integrated into clinical pathways for the detection, characterization, and staging of malignant tumors including those arising in the musculoskeletal (MSK) system. Although further developments and research are needed, it is now recognized that WB-MRI enables reliable, sensitive, and specific detection and quantification of disease burden, with clinical applications for a variety of disease types and a particular application for skeletal involvement. Advances in imaging techniques now allow the reliable incorporation of WB-MRI into clinical pathways, and guidelines recommending its use are emerging. This review assesses the benefits, clinical applications, limitations, and future capabilities of WB-MRI in the context of other next-generation imaging modalities, as a qualitative and quantitative tool for the detection and characterization of skeletal and soft tissue MSK malignancies.
KW - bone metastasis
KW - myeloma
KW - next-generation imaging
KW - precision oncology
KW - whole-body MRI
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U2 - 10.1055/s-0040-1719018
DO - 10.1055/s-0040-1719018
M3 - Article
C2 - 33307587
AN - SCOPUS:85098084254
SN - 1089-7860
VL - 24
SP - 726
EP - 749
JO - Seminars in Musculoskeletal Radiology
JF - Seminars in Musculoskeletal Radiology
IS - 6
ER -