Design and development of a co-planar fluorescence and X-ray tomograph

Juan Aguirre; Alejandro Sisniega; Jorge Ripoll; Manuel Desco; Juan José Vaquero

doi:10.1109/NSSMIC.2008.4774456

Design and development of a co-planar fluorescence and X-ray tomograph

Juan Aguirre, Alejandro Sisniega, Jorge Ripoll, Manuel Desco, Juan José Vaquero

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Scopus citations

Abstract

Non-contact Fluorescence Diffuse Optical Tomography (FDOT) is rapidly becoming an important tool for small animal research, since it is able to display the 3D distribution of near infrared fluorescent probes in the whole body. FDOT, like other functional and molecular imaging techniques (PET, SPECT), lacks anatomical information, limiting the resolution of analyses of living systems. Furthermore, anatomical information from the subject under study can be used as a priori information for the FDOT reconstruction algorithm to improve its performance. With these goals in mind, we have built a proof-of-concept FDOT-CT hybrid machine that combines the high-resolution anatomy of CT with the functional information provided by FDOT.

Original language	English (US)
Title of host publication	2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Pages	5412-5413
Number of pages	2
DOIs	https://doi.org/10.1109/NSSMIC.2008.4774456
State	Published - 2008
Externally published	Yes
Event	2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 - Dresden, Germany Duration: Oct 19 2008 → Oct 25 2008

Publication series

Name	IEEE Nuclear Science Symposium Conference Record
ISSN (Print)	1095-7863

Other

Other	2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Country/Territory	Germany
City	Dresden
Period	10/19/08 → 10/25/08

ASJC Scopus subject areas

Radiation
Nuclear and High Energy Physics
Radiology Nuclear Medicine and imaging

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10.1109/NSSMIC.2008.4774456

Cite this

Aguirre, J, Sisniega, A, Ripoll, J, Desco, M & Vaquero, JJ 2008, Design and development of a co-planar fluorescence and X-ray tomograph. in 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008., 4774456, IEEE Nuclear Science Symposium Conference Record, pp. 5412-5413, 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008, Dresden, Germany, 10/19/08. https://doi.org/10.1109/NSSMIC.2008.4774456

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title = "Design and development of a co-planar fluorescence and X-ray tomograph",

abstract = "Non-contact Fluorescence Diffuse Optical Tomography (FDOT) is rapidly becoming an important tool for small animal research, since it is able to display the 3D distribution of near infrared fluorescent probes in the whole body. FDOT, like other functional and molecular imaging techniques (PET, SPECT), lacks anatomical information, limiting the resolution of analyses of living systems. Furthermore, anatomical information from the subject under study can be used as a priori information for the FDOT reconstruction algorithm to improve its performance. With these goals in mind, we have built a proof-of-concept FDOT-CT hybrid machine that combines the high-resolution anatomy of CT with the functional information provided by FDOT.",

author = "Juan Aguirre and Alejandro Sisniega and Jorge Ripoll and Manuel Desco and Vaquero, {Juan Jos{\'e}}",

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AU - Aguirre, Juan

AU - Sisniega, Alejandro

AU - Ripoll, Jorge

AU - Desco, Manuel

AU - Vaquero, Juan José

PY - 2008

Y1 - 2008

N2 - Non-contact Fluorescence Diffuse Optical Tomography (FDOT) is rapidly becoming an important tool for small animal research, since it is able to display the 3D distribution of near infrared fluorescent probes in the whole body. FDOT, like other functional and molecular imaging techniques (PET, SPECT), lacks anatomical information, limiting the resolution of analyses of living systems. Furthermore, anatomical information from the subject under study can be used as a priori information for the FDOT reconstruction algorithm to improve its performance. With these goals in mind, we have built a proof-of-concept FDOT-CT hybrid machine that combines the high-resolution anatomy of CT with the functional information provided by FDOT.

AB - Non-contact Fluorescence Diffuse Optical Tomography (FDOT) is rapidly becoming an important tool for small animal research, since it is able to display the 3D distribution of near infrared fluorescent probes in the whole body. FDOT, like other functional and molecular imaging techniques (PET, SPECT), lacks anatomical information, limiting the resolution of analyses of living systems. Furthermore, anatomical information from the subject under study can be used as a priori information for the FDOT reconstruction algorithm to improve its performance. With these goals in mind, we have built a proof-of-concept FDOT-CT hybrid machine that combines the high-resolution anatomy of CT with the functional information provided by FDOT.

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Design and development of a co-planar fluorescence and X-ray tomograph

Abstract

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ASJC Scopus subject areas

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