Defining the Role of Astrocytes in Neuromodulation

Nicolas X. Tritsch; Dwight E. Bergles

doi:10.1016/j.neuron.2007.05.008

Defining the Role of Astrocytes in Neuromodulation

Nicolas X. Tritsch, Dwight E. Bergles

School of Medicine

Research output: Contribution to journal › Short survey › peer-review

19 Scopus citations

Abstract

Astrocytes undergo elevations in intracellular calcium following activation of metabotropic receptors, which may trigger glutamate secretion and excitation of surrounding neurons. In this issue of Neuron, Fiacco et al. use transgenic mice that express a foreign G_q-coupled receptor in astrocytes to show that selective stimulation of astrocytes is not sufficient to induce the release of glutamate.

Original language	English (US)
Pages (from-to)	497-500
Number of pages	4
Journal	Neuron
Volume	54
Issue number	4
DOIs	https://doi.org/10.1016/j.neuron.2007.05.008
State	Published - May 24 2007

ASJC Scopus subject areas

General Neuroscience

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10.1016/j.neuron.2007.05.008

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title = "Defining the Role of Astrocytes in Neuromodulation",

abstract = "Astrocytes undergo elevations in intracellular calcium following activation of metabotropic receptors, which may trigger glutamate secretion and excitation of surrounding neurons. In this issue of Neuron, Fiacco et al. use transgenic mice that express a foreign Gq-coupled receptor in astrocytes to show that selective stimulation of astrocytes is not sufficient to induce the release of glutamate.",

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Defining the Role of Astrocytes in Neuromodulation

Abstract

ASJC Scopus subject areas

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