Defining new surrogate markers for CKD progression

H. William Schnaper; Susan L. Furth; Lynne P. Yao

doi:10.1007/s00467-014-2995-0

Defining new surrogate markers for CKD progression

H. William Schnaper, Susan L. Furth, Lynne P. Yao

School of Medicine

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.

Original language	English (US)
Pages (from-to)	193-198
Number of pages	6
Journal	Pediatric Nephrology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1007/s00467-014-2995-0
State	Published - Nov 5 2015

Keywords

Chronic kidney disease
GFR
Kidney function
Locusta migratoria
Pediatric CKD
Surrogate markers

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Nephrology

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title = "Defining new surrogate markers for CKD progression",

abstract = "At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.",

keywords = "Chronic kidney disease, GFR, Kidney function, Locusta migratoria, Pediatric CKD, Surrogate markers",

author = "{William Schnaper}, H. and Furth, {Susan L.} and Yao, {Lynne P.}",

note = "Funding Information: We appreciate thoughtful comments on the manuscript by Aliza Thompson. This work was supported in part by grants R01-DK049362 (to H.W.S.), and K24-DK078737 and U01-DK066174 (to S.L.F.) from the National Institute of Diabetes, Digestive and Kidney Diseases. Publisher Copyright: {\textcopyright} 2014 IPNA.",

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T1 - Defining new surrogate markers for CKD progression

AU - William Schnaper, H.

AU - Furth, Susan L.

AU - Yao, Lynne P.

N1 - Funding Information: We appreciate thoughtful comments on the manuscript by Aliza Thompson. This work was supported in part by grants R01-DK049362 (to H.W.S.), and K24-DK078737 and U01-DK066174 (to S.L.F.) from the National Institute of Diabetes, Digestive and Kidney Diseases. Publisher Copyright: © 2014 IPNA.

PY - 2015/11/5

Y1 - 2015/11/5

N2 - At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.

AB - At a recent meeting of international experts on clinical aspects of progressive chronic kidney disease (CKD), an extensive analysis of extant clinical trials was used to develop more effective and economical surrogate markers for CKD outcomes in adults. This article describes the reasons for this undertaking, the methods and conclusions of the meeting, and the relevance of these findings to pediatric nephrology.

KW - Chronic kidney disease

KW - GFR

KW - Kidney function

KW - Locusta migratoria

KW - Pediatric CKD

KW - Surrogate markers

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Defining new surrogate markers for CKD progression

Abstract

Keywords

ASJC Scopus subject areas

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