Abstract
The following paper on gastroesophageal reflux disease (GERD) and Barrett's esophagus (BE) includes commentaries on defining esophageal landmarks; new techniques for evaluating upper esophageal sphincter (UES) tone; differential diagnosis of GERD, BE, and hiatal hernia (HH); the use of high-resolution manometry for evaluation of reflux; the role of fundic relaxation in reflux; the use of 24-h esophageal pH-impedance testing in differentiating acid from nonacid reflux and its potential inclusion in future Rome criteria; classification of endoscopic findings in GERD; the search for the cell origin that generates BE; and the relationship between BE, Barrett's carcinoma, and obesity.
Original language | English (US) |
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Pages (from-to) | 278-295 |
Number of pages | 18 |
Journal | Annals of the New York Academy of Sciences |
Volume | 1300 |
Issue number | 1 |
DOIs | |
State | Published - Oct 2013 |
Externally published | Yes |
Keywords
- Dysphagia
- Endoscopy
- GERD
- Manometry
- NERD
ASJC Scopus subject areas
- Neuroscience(all)
- Biochemistry, Genetics and Molecular Biology(all)
- History and Philosophy of Science