Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13

Fred Funk; Stanley Person

doi:10.1126/science.166.3913.1629

Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13

Fred Funk, Stanley Person

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Decay of cytosine-5-³H incorporated into bacteriophage S13 DNA causes a molecular rearrangement of the cytosine molecule undergoing the decay. The molecular rearrangement produces a cytosine to thymine coding change with an efficiency approaching one. Decay of either thymidine-(methyl)-³H or cytosine-6-³H is less than 1 percent as effective in causing either cytosine to thymine or thymine to cytosine transitions.

Original language	English (US)
Pages (from-to)	1629-1631
Number of pages	3
Journal	Science
Volume	166
Issue number	3913
DOIs	https://doi.org/10.1126/science.166.3913.1629
State	Published - 1969
Externally published	Yes

ASJC Scopus subject areas

General

Access to Document

10.1126/science.166.3913.1629

Cite this

@article{df0a98d2a13345d4a2baeae15067f2a4,

title = "Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13",

abstract = "Decay of cytosine-5-3H incorporated into bacteriophage S13 DNA causes a molecular rearrangement of the cytosine molecule undergoing the decay. The molecular rearrangement produces a cytosine to thymine coding change with an efficiency approaching one. Decay of either thymidine-(methyl)-3H or cytosine-6-3H is less than 1 percent as effective in causing either cytosine to thymine or thymine to cytosine transitions.",

author = "Fred Funk and Stanley Person",

year = "1969",

doi = "10.1126/science.166.3913.1629",

language = "English (US)",

volume = "166",

pages = "1629--1631",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "3913",

}

TY - JOUR

T1 - Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13

AU - Funk, Fred

AU - Person, Stanley

PY - 1969

Y1 - 1969

N2 - Decay of cytosine-5-3H incorporated into bacteriophage S13 DNA causes a molecular rearrangement of the cytosine molecule undergoing the decay. The molecular rearrangement produces a cytosine to thymine coding change with an efficiency approaching one. Decay of either thymidine-(methyl)-3H or cytosine-6-3H is less than 1 percent as effective in causing either cytosine to thymine or thymine to cytosine transitions.

AB - Decay of cytosine-5-3H incorporated into bacteriophage S13 DNA causes a molecular rearrangement of the cytosine molecule undergoing the decay. The molecular rearrangement produces a cytosine to thymine coding change with an efficiency approaching one. Decay of either thymidine-(methyl)-3H or cytosine-6-3H is less than 1 percent as effective in causing either cytosine to thymine or thymine to cytosine transitions.

UR - http://www.scopus.com/inward/record.url?scp=0014692210&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0014692210&partnerID=8YFLogxK

U2 - 10.1126/science.166.3913.1629

DO - 10.1126/science.166.3913.1629

M3 - Article

C2 - 5360583

AN - SCOPUS:0014692210

SN - 0036-8075

VL - 166

SP - 1629

EP - 1631

JO - Science

JF - Science

IS - 3913

ER -

Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this