Cytoreductive surgery and intraperitoneal chemotherapy for the treatment of peritoneal surface malignancy

C. Pablo Carmignani, Jesús Esquivel, Paul H. Sugarbaker

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Despite new developments in the treatment of solid tumors, complete resection remains as an absolute requirement for cure of gastrointestinal cancer. Success in the surgical management of peritoneal surface malignancy depends on the surgeon's ability to complete complex cytoreductive procedures so that only microscopic disease remains. This paper describes the current strategy that the surgical oncologist should pursue in the treatment of patients with peritoneal carcinomatosis, sarcomatosis and mesothelioma. Technical details required for this surgery include patient position, incision and exposure, complete lysis of adhesions, electroevaporative dissection, peritonectomy procedures, proper positioning of drains for intraperitoneal chemotherapy, and reconstructive surgery. Understanding the treatment and mastery of surgical skills to manage the peritoneal surface spread of malignancy has led to long-term survival of selected patients. The success of this treatment strategy depends on a long-term dedication to achieve the full potential of a curative outcome.

Original languageEnglish (US)
Pages (from-to)192-198
Number of pages7
JournalClinical and Translational Oncology
Issue number4
StatePublished - May 2003


  • Cytoreductive surgery
  • Intraperitoneal chemotherapy
  • Peritoneal carcinomatosis

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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