Cytology of cervical chordoma in cerebrospinal fluid from a child: A case report

S. Z. Ali, S. B. Semmelmeier, C. Urmacher

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The cytologic findings on cerebrospinal fluid examination of cervical chordoma in a 2-year-old girl are presented. The major cell type was a small, isolated, hyperchromatic cell with sharply defined nuclear membrane and granular cytoplasm. However, the characteristic cell of this neoplasm, the so-called physaliferous cell with typical bubbly cytoplasm, was also noted. Cytologic findings were compared to biopsy findings, with a good correlation of tumor morphology. Clinical follow-up revealed unusually aggressive tumor behavior, and the patient died a year later despite intensive chemotherapy. The differential diagnosis of the condition is also discussed.

Original languageEnglish (US)
Pages (from-to)766-769
Number of pages4
JournalActa cytologica
Issue number4
StatePublished - 1995
Externally publishedYes


  • cerebrospinal fluid
  • chordoma
  • neck neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology


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