TY - CHAP
T1 - Cysteine proteases from bloodfeeding arthropod ectoparasites
AU - Sojka, Daniel
AU - Francischetti, Ivo M.B.
AU - Calvo, Eric
AU - Kotsyfakis, Michalis
PY - 2011
Y1 - 2011
N2 - Cysteine proteases have been discovered in various bloodfeeding ectoparasites. Here, we assemble the available information about the function of these peptidases and reveal their role in hematophagy and parasite development. While most of the data shed light on key proteolytic events that play a role in arthropod physiology, we also report on the association of cysteine proteases with arthropod vectorial capacity. With emphasis on ticks, specifically Ixodes ricinus, we finally propose a model about the contribution of cysteine peptidases to blood digestion and how their concerted action with other tick midgut proteases leads to the absorbance of nutrients by the midgut epithelial cells.
AB - Cysteine proteases have been discovered in various bloodfeeding ectoparasites. Here, we assemble the available information about the function of these peptidases and reveal their role in hematophagy and parasite development. While most of the data shed light on key proteolytic events that play a role in arthropod physiology, we also report on the association of cysteine proteases with arthropod vectorial capacity. With emphasis on ticks, specifically Ixodes ricinus, we finally propose a model about the contribution of cysteine peptidases to blood digestion and how their concerted action with other tick midgut proteases leads to the absorbance of nutrients by the midgut epithelial cells.
UR - https://www.scopus.com/pages/publications/80053297181
UR - https://www.scopus.com/pages/publications/80053297181#tab=citedBy
U2 - 10.1007/978-1-4419-8414-2_11
DO - 10.1007/978-1-4419-8414-2_11
M3 - Chapter
C2 - 21660665
AN - SCOPUS:80053297181
SN - 9781441984135
T3 - Advances in Experimental Medicine and Biology
SP - 177
EP - 191
BT - Cysteine Proteases of Pathogenic Organisms
A2 - Robinson, Mark
A2 - Dalton, John
ER -