Cyclin' on the viral path to destruction

J. M. Hardwick

doi:10.1038/35041126

Cyclin' on the viral path to destruction

J. M. Hardwick

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

8 Scopus citations

Abstract

Viruses are the masters of trickery. They mimic, manipulate and usurp cellular functions, but always with an interesting twist. γ-herpesvirus genomes encode an abundance of homologues of cellular factors, including cyclin and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins have gained new functions and eliminated others to harness the cell and benefit the virus.

Original language	English (US)
Pages (from-to)	E203-E204
Journal	Nature cell biology
Volume	2
Issue number	11
DOIs	https://doi.org/10.1038/35041126
State	Published - Nov 20 2000

ASJC Scopus subject areas

Cell Biology

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abstract = "Viruses are the masters of trickery. They mimic, manipulate and usurp cellular functions, but always with an interesting twist. γ-herpesvirus genomes encode an abundance of homologues of cellular factors, including cyclin and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins have gained new functions and eliminated others to harness the cell and benefit the virus.",

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AB - Viruses are the masters of trickery. They mimic, manipulate and usurp cellular functions, but always with an interesting twist. γ-herpesvirus genomes encode an abundance of homologues of cellular factors, including cyclin and Bcl-2. These viral homologues differ from their cellular counterparts in that the viral proteins have gained new functions and eliminated others to harness the cell and benefit the virus.

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Cyclin' on the viral path to destruction

Abstract

ASJC Scopus subject areas

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