Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness

Peggy M. Cawthon; Katherine W. Peters; Michelle D. Shardell; Robert R. McLean; Thuy Tien L Dam; Anne M. Kenny; Maren S. Fragala; Tamara B. Harris; Douglas P. Kiel; Jack M. Guralnik; Luigi Ferrucci; Stephen B. Kritchevsky; Maria T. Vassileva; Stephanie A. Studenski; Dawn E. Alley

doi:10.1093/gerona/glu023

Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness

Peggy M. Cawthon, Katherine W. Peters, Michelle D. Shardell, Robert R. McLean, Thuy Tien L Dam, Anne M. Kenny, Maren S. Fragala, Tamara B. Harris, Douglas P. Kiel, Jack M. Guralnik, Luigi Ferrucci, Stephen B. Kritchevsky, Maria T. Vassileva, Stephanie A. Studenski, Dawn E. Alley

Research output: Contribution to journal › Article › peer-review

191 Scopus citations

Abstract

Background.Low lean mass is potentially clinically important in older persons, but criteria have not been empirically validated. As part of the FNIH (Foundation for the National Institutes of Health) Sarcopenia Project, this analysis sought to identify cutpoints in lean mass by dual-energy x-ray absorptiometry that discriminate the presence or absence of weakness (defined in a previous report in the series as grip strength BMI) identified a secondary definition (ALM_BMI BMI

Original language	English (US)
Pages (from-to)	567-575
Number of pages	9
Journal	Journals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume	69 A
Issue number	5
DOIs	https://doi.org/10.1093/gerona/glu023
State	Published - 2014
Externally published	Yes

Keywords

Cutpoints.
Muscle
Sarcopenia

ASJC Scopus subject areas

Aging
Geriatrics and Gerontology
Medicine(all)

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10.1093/gerona/glu023

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Cawthon, P. M., Peters, K. W., Shardell, M. D., McLean, R. R., Dam, T. T. L., Kenny, A. M., Fragala, M. S., Harris, T. B., Kiel, D. P., Guralnik, J. M., Ferrucci, L., Kritchevsky, S. B., Vassileva, M. T., Studenski, S. A., & Alley, D. E. (2014). Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness. Journals of Gerontology - Series A Biological Sciences and Medical Sciences, 69 A(5), 567-575. https://doi.org/10.1093/gerona/glu023

Cawthon, PM, Peters, KW, Shardell, MD, McLean, RR, Dam, TTL, Kenny, AM, Fragala, MS, Harris, TB, Kiel, DP, Guralnik, JM, Ferrucci, L, Kritchevsky, SB, Vassileva, MT, Studenski, SA & Alley, DE 2014, 'Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness', Journals of Gerontology - Series A Biological Sciences and Medical Sciences, vol. 69 A, no. 5, pp. 567-575. https://doi.org/10.1093/gerona/glu023

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abstract = "Background.Low lean mass is potentially clinically important in older persons, but criteria have not been empirically validated. As part of the FNIH (Foundation for the National Institutes of Health) Sarcopenia Project, this analysis sought to identify cutpoints in lean mass by dual-energy x-ray absorptiometry that discriminate the presence or absence of weakness (defined in a previous report in the series as grip strength BMI) identified a secondary definition (ALMBMI BMI ",

keywords = "Cutpoints., Muscle, Sarcopenia",

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year = "2014",

doi = "10.1093/gerona/glu023",

language = "English (US)",

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AU - Cawthon, Peggy M.

AU - Peters, Katherine W.

AU - Shardell, Michelle D.

AU - McLean, Robert R.

AU - Dam, Thuy Tien L

AU - Kenny, Anne M.

AU - Fragala, Maren S.

AU - Harris, Tamara B.

AU - Kiel, Douglas P.

AU - Guralnik, Jack M.

AU - Ferrucci, Luigi

AU - Kritchevsky, Stephen B.

AU - Vassileva, Maria T.

AU - Studenski, Stephanie A.

AU - Alley, Dawn E.

PY - 2014

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KW - Cutpoints.

KW - Muscle

KW - Sarcopenia

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Cutpoints for low appendicular lean mass that identify older adults with clinically significant weakness

Abstract

Keywords

ASJC Scopus subject areas

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