Current controversies in the surgical management of pancreatic cancer

Ammar Asrar Javed, Kanza Aziz, Christopher Lee Wolfgang

Research output: Chapter in Book/Report/Conference proceedingChapter


Pancreatic ductal adenocarcinoma is one of the deadliest malignancies with an extremely poor survival rate. Both environmental and hereditary factors play a role in the development of disease, and early diagnosis is difficult due to early systemic involvement of disease. Thus, a majority of patients are not surgical candidates at the time of diagnosis. The treatment of pancreatic cancer is dependent on the stage of disease. Several controversies exist that are relevant to surgery. These include: (1) the use of diagnostic laparoscopy, (2) surgery-first versus neoadjuvant approach, (3) definition of borderline resectable, and (4) ablative therapies for locally unresectable pancreatic cancer. This chapter discusses the current principles of the management related to these topics and their variation across different centers and physicians treating pancreatic cancer.

Original languageEnglish (US)
Title of host publicationCurrent Controversies in Cancer Care for the Surgeon
PublisherSpringer International Publishing
Number of pages12
ISBN (Electronic)9783319162058
ISBN (Print)9783319162041
StatePublished - Jan 1 2015


  • Ablation
  • Borderline resectable
  • Controversies
  • Diagnostic laparoscopy
  • Management
  • Neoadjuvant therapy
  • Pancreatectomy
  • Pancreatic adenocarcinoma
  • Pancreatic cancer
  • Resectability

ASJC Scopus subject areas

  • General Medicine


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