Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc; Zina Meriden; Deanna A. Sutton; Elizabeth H. Thompson; Dionissios Neofytos; Sean X. Zhang

doi:10.1016/j.diagmicrobio.2013.03.009

Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc
, Zina Meriden
, Deanna A. Sutton
, Elizabeth H. Thompson
, Dionissios Neofytos
, Sean X. Zhang

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

Original language	English (US)
Pages (from-to)	506-509
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	76
Issue number	4
DOIs	https://doi.org/10.1016/j.diagmicrobio.2013.03.009
State	Published - Aug 2013

Keywords

Angioinvasion
Cunninghamella
Cunninghamella echinulata
Febrile neutropenia
Filamentous fungi
Invasive fungal infection
Leukemia
Sinusitis
Zygomycetes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.diagmicrobio.2013.03.009

Cite this

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title = "Cunninghamella echinulata causing fatally invasive fungal sinusitis",

abstract = "We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.",

keywords = "Angioinvasion, Cunninghamella, Cunninghamella echinulata, Febrile neutropenia, Filamentous fungi, Invasive fungal infection, Leukemia, Sinusitis, Zygomycetes",

author = "LeBlanc, \{Robert E.\} and Zina Meriden and Sutton, \{Deanna A.\} and Thompson, \{Elizabeth H.\} and Dionissios Neofytos and Zhang, \{Sean X.\}",

year = "2013",

month = aug,

doi = "10.1016/j.diagmicrobio.2013.03.009",

language = "English (US)",

volume = "76",

pages = "506--509",

journal = "Diagnostic Microbiology and Infectious Disease",

issn = "0732-8893",

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}

TY - JOUR

T1 - Cunninghamella echinulata causing fatally invasive fungal sinusitis

AU - LeBlanc, Robert E.

AU - Meriden, Zina

AU - Sutton, Deanna A.

AU - Thompson, Elizabeth H.

AU - Neofytos, Dionissios

AU - Zhang, Sean X.

PY - 2013/8

Y1 - 2013/8

N2 - We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

AB - We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

KW - Angioinvasion

KW - Cunninghamella

KW - Cunninghamella echinulata

KW - Febrile neutropenia

KW - Filamentous fungi

KW - Invasive fungal infection

KW - Leukemia

KW - Sinusitis

KW - Zygomycetes

UR - https://www.scopus.com/pages/publications/84880729141

UR - https://www.scopus.com/pages/publications/84880729141#tab=citedBy

U2 - 10.1016/j.diagmicrobio.2013.03.009

DO - 10.1016/j.diagmicrobio.2013.03.009

M3 - Article

C2 - 23602784

AN - SCOPUS:84880729141

SN - 0732-8893

VL - 76

SP - 506

EP - 509

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

IS - 4

ER -

Cunninghamella echinulata causing fatally invasive fungal sinusitis

Abstract

Keywords

ASJC Scopus subject areas

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