Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc; Zina Meriden; Deanna A. Sutton; Elizabeth H. Thompson; Dionissios Neofytos; Sean X. Zhang

doi:10.1016/j.diagmicrobio.2013.03.009

Cunninghamella echinulata causing fatally invasive fungal sinusitis

Robert E. LeBlanc, Zina Meriden, Deanna A. Sutton, Elizabeth H. Thompson, Dionissios Neofytos, Sean X. Zhang

School of Medicine

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

Original language	English (US)
Pages (from-to)	506-509
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	76
Issue number	4
DOIs	https://doi.org/10.1016/j.diagmicrobio.2013.03.009
State	Published - Aug 2013

Keywords

Angioinvasion
Cunninghamella
Cunninghamella echinulata
Febrile neutropenia
Filamentous fungi
Invasive fungal infection
Leukemia
Sinusitis
Zygomycetes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.diagmicrobio.2013.03.009

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title = "Cunninghamella echinulata causing fatally invasive fungal sinusitis",

abstract = "We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.",

keywords = "Angioinvasion, Cunninghamella, Cunninghamella echinulata, Febrile neutropenia, Filamentous fungi, Invasive fungal infection, Leukemia, Sinusitis, Zygomycetes",

author = "LeBlanc, {Robert E.} and Zina Meriden and Sutton, {Deanna A.} and Thompson, {Elizabeth H.} and Dionissios Neofytos and Zhang, {Sean X.}",

year = "2013",

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doi = "10.1016/j.diagmicrobio.2013.03.009",

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pages = "506--509",

journal = "Diagnostic Microbiology and Infectious Disease",

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T1 - Cunninghamella echinulata causing fatally invasive fungal sinusitis

AU - LeBlanc, Robert E.

AU - Meriden, Zina

AU - Sutton, Deanna A.

AU - Thompson, Elizabeth H.

AU - Neofytos, Dionissios

AU - Zhang, Sean X.

PY - 2013/8

Y1 - 2013/8

N2 - We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

AB - We report a fatal case of invasive fungal sinusitis caused by Cunninghamella echinulata in a febrile, neutropenic 15-year-old male with relapsing acute leukemia. The isolate was recovered from a nasal biopsy from the right middle meatus, and microscopic examination of the tissue revealed angioinvasion and necrosis. Human infection caused by this organism has not been well documented; however, this report alerts us to its life-threatening potential.

KW - Angioinvasion

KW - Cunninghamella

KW - Cunninghamella echinulata

KW - Febrile neutropenia

KW - Filamentous fungi

KW - Invasive fungal infection

KW - Leukemia

KW - Sinusitis

KW - Zygomycetes

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M3 - Article

C2 - 23602784

AN - SCOPUS:84880729141

SN - 0732-8893

VL - 76

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JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

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ER -

Cunninghamella echinulata causing fatally invasive fungal sinusitis

Abstract

Keywords

ASJC Scopus subject areas

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