CT Perfusion: Ready for prime time

Marietta S. Ambrose, Carolina Valdiviezo, Vishal Mehra, Albert C. Lardo, Joao A.C. Lima, Richard T. George

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Advancements in computed tomography (CT) technology have revolutionized clinical practice, particularly regarding the noninvasive assessment of coronary artery disease (CAD). The versatility of cardiac CT has rendered multiple applications including assessment of cardiac structure and function, myocardial viability, and coronary anatomy. The merits of cardiac computed tomography angiography (CTA) have been proven for the detection, and particularly the exclusion, of CAD. However, CTA becomes limited in the presence of significant CAD. Its inability to consistently identify lesion-associated ischemia may necessitate additional radionuclide myocardial perfusion imaging. Myocardial computed tomography perfusion imaging (CTP) has emerged as a useful and convenient method to immediately assess myocardial ischemia. In this review, we discuss the current state of CTP including available technology, its performance to date from current literature, and future challenges to this field.

Original languageEnglish (US)
Pages (from-to)57-66
Number of pages10
JournalCurrent Cardiology Reports
Issue number1
StatePublished - Feb 2011


  • CAD
  • CT perfusion imaging
  • CTA
  • Cardiac stress test
  • Coronary
  • Dual-source CT
  • Dynamic CT
  • Helical CT
  • MDCT
  • Myocardial blood flow
  • Myocardial perfusion
  • Noninvasive testing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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