CSF copper concentrations in chronic schizophrenia

D. Shore, S. G. Potkin, D. R. Weinberger, E. F. Torrey, R. I. Henkin, R. P. Agarwal, J. C. Gillin, R. J. Wyatt

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The authors used a sensitive flameless atomic absorption spectrophotometric procedure to measure CSF copper concentrations in normal controls, former heroin addicts, and unmedicated and medicated chronic schizophrenic patients and found no significant differences in CSF copper levels between these groups. Schizophrenic women had significantly lower CSF copper levels than schizophrenic men, but no significant differences were found between control men and control women. There were no differences in CSF copper levels between patient subgroups with respect to diagnostic subtype (acute versus chronic, paranoid versus chronic undifferentiated), length of hospitalization, race, medication status, platelet monoamine oxidase values, or CAT scan abnormalities.

Original languageEnglish (US)
Pages (from-to)754-757
Number of pages4
JournalUnknown Journal
Issue number6
StatePublished - Jan 1 1983
Externally publishedYes

ASJC Scopus subject areas

  • Psychiatry and Mental health


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