Crossbridge dynamics in muscle contraction

A. Landesberg, R. Beyar, S. Sideman, H. E D J Ter Keurs, J. Solaro, D. Burkhoff

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


The study deals with the description of muscle contraction based on biochemical studies and describes four major approaches for coupling calcium kinetics with crossbridge (Xb) cycling. The analysis illuminates two controversial points: 1) the relationship between Xb attachment/detachment and Xb cycling, i.e., the transition between weak to strong conformations, and 2) the effect of calcium on Xb function: does it regulate Xb kinetics or Xb recruitment.

Original languageEnglish (US)
Pages (from-to)137-153
Number of pages17
JournalAdvances in Experimental Medicine and Biology
StatePublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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