COVID vaccine–induced lupus nephritis: Case report and review of the literature

Antonio Salas; Ayotola Fatola; Rebecca Krimins; Ihab R. Kamel; Duvuru Geetha; Derek Fine; Manny Monroy-Trujillo; Avi Rosenberg; Lois Arend; Homa Timlin

doi:10.1177/09612033231222390

COVID vaccine–induced lupus nephritis: Case report and review of the literature

Antonio Salas, Ayotola Fatola, Rebecca Krimins, Ihab R. Kamel, Duvuru Geetha, Derek Fine, Manny Monroy-Trujillo, Avi Rosenberg, Lois Arend, Homa Timlin

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Vaccines offer an effective strategy to prevent infectious diseases with minimal adverse effects. On rare occasions, vaccination can disrupt the immune response leading to induction of autoimmune diseases. We describe a case of new-onset lupus nephritis following COVID-19 vaccination with the first dose of the Pfizer vaccine. Her symptoms and lab values improved with steroids, hydroxychloroquine, and mycophenolate mofetil.

Original language	English (US)
Pages (from-to)	176-182
Number of pages	7
Journal	Lupus
Volume	33
Issue number	2
DOIs	https://doi.org/10.1177/09612033231222390
State	Published - Feb 2024

Keywords

COVID vaccine
Systemic lupus erythematosus
lupus nephritis

ASJC Scopus subject areas

Rheumatology

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10.1177/09612033231222390

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title = "COVID vaccine–induced lupus nephritis: Case report and review of the literature",

abstract = "Vaccines offer an effective strategy to prevent infectious diseases with minimal adverse effects. On rare occasions, vaccination can disrupt the immune response leading to induction of autoimmune diseases. We describe a case of new-onset lupus nephritis following COVID-19 vaccination with the first dose of the Pfizer vaccine. Her symptoms and lab values improved with steroids, hydroxychloroquine, and mycophenolate mofetil.",

keywords = "COVID vaccine, Systemic lupus erythematosus, lupus nephritis",

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AU - Geetha, Duvuru

AU - Fine, Derek

AU - Monroy-Trujillo, Manny

AU - Rosenberg, Avi

AU - Arend, Lois

AU - Timlin, Homa

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AB - Vaccines offer an effective strategy to prevent infectious diseases with minimal adverse effects. On rare occasions, vaccination can disrupt the immune response leading to induction of autoimmune diseases. We describe a case of new-onset lupus nephritis following COVID-19 vaccination with the first dose of the Pfizer vaccine. Her symptoms and lab values improved with steroids, hydroxychloroquine, and mycophenolate mofetil.

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KW - Systemic lupus erythematosus

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COVID vaccine–induced lupus nephritis: Case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

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