COVID-19 related pancreatic cancer surveillance disruptions amongst high-risk individuals

Bryson W. Katona, Nadim Mahmud, Mohamad Dbouk, Nuzhat Ahmad, Ankit Chhoda, Beth Dudley, Umar Hayat, Richard S. Kwon, Linda S. Lee, Anil K. Rustgi, Chinedu Ukaegbu, Lisa Vasquez, Sarah Volk, Randall E. Brand, Marcia I. Canto, Amitabh Chak, James J. Farrell, Fay Kastrinos, Elena M. Stoffel, Sapna SyngalMichael Goggins

Research output: Contribution to journalArticlepeer-review


Background: COVID-19 pandemic-related disruptions to EUS-based pancreatic cancer surveillance in high-risk individuals remain uncertain. Methods: Analysis of enrolled participants in the CAPS5 Study, a prospective multicenter study of pancreatic cancer surveillance in high-risk individuals. Results: Amongst 693 enrolled high-risk individuals under active surveillance, 108 (16%) had an EUS scheduled during the COVID-19 pandemic-related shutdown (median length of 78 days) in the spring of 2020, with 97% of these procedures being canceled. Of these canceled surveillance EUSs, 83% were rescheduled in a median of 4.1 months, however 17% were not rescheduled after 6 months follow-up. Prior history of cancer was associated with increased likelihood of rescheduling. To date no pancreatic cancer has been diagnosed among those whose surveillance was delayed. Conclusions: COVID-19 delayed pancreatic cancer surveillance with no adverse outcomes in efficiently rescheduled individuals. However, 1 in 6 high-risk individuals had not rescheduled surveillance, indicating the need for vigilance to ensure timely surveillance rescheduling.

Original languageEnglish (US)
Pages (from-to)1048-1051
Number of pages4
Issue number6
StatePublished - Sep 2021


  • COVID-19
  • EUS
  • Pancreatic cancer
  • Surveillance

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Hepatology


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